| Nonlagged relay cells and interneurons in the cat lateral geniculate nucleus: receptive-field properties and retinal inputs. | |
| | |
MedLine Citation:
|
PMID: 1586644 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
Simultaneous recording in the cat's retina and lateral geniculate nucleus (LGN) was used to find excitatory inputs to LGN cells. These recordings, correlated with measurements of LGN cell receptive-field properties, suggested new functional subdivisions of LGN cells. Distinctions between lagged and nonlagged cells were described before (Mastronarde, 1987a,b; Mastronarde et al., 1991), classification of nonlagged cells is examined here. The XS-type relay cells described before (Mastronarde, 1987a,b) each had detectable excitatory input from only one retinal X cell. Cells that received significant input from more than one retinal X cell were of three kinds: relay cells with pure X input (XM); relay cells with mixed X and Y input (X/Y); and cells that could not be antidromically activated from visual cortex (XI). In the series of relay cells, XS-XM-X/Y-Y, cells had progressively larger receptive-field centers, lower spatial resolution, and faster and more Y-like responses to various stimuli. XI cells resembled XM and X/Y cells in some respects but tended to have higher maintained firing rates, more sustained responses, and weaker surround suppression of the center response. The distinctness of XS, XM, X/Y, XI, and Y from each other was examined with a modification of discriminant analysis that allowed cells to lack measurements for some parameters. Any given pair of categories could be distinguished reliably with only three parameters, although less so for X/Y-Y. In particular, XI cells were distinguishable from relay cells by properties other than the results of cortical stimulation, thus supporting the identity of XI cells as a separate class of X interneurons. Two discontinuities in the behavior of retinal input suggest that XM cells are a separate class from XS and X/Y cells: (1) LGN X cells received either no detectable input from any of the retinal X cells adjacent to their main input, or an easily detectable amount from several such cells; and (2) cells received either no Y input or a certain minimum amount. No such discontinuity in input underlies the distinction between X/Y and Y cells. LGN Y cells were also heterogeneous. Those with substantial input from more than one retinal Y cell had larger receptive fields and a greater preference for fast-moving stimuli than did Y cells dominated by a single input. Three Y cells could not be antidromically activated. They tended to differ from Y relay cells and resemble X interneurons in several ways.(ABSTRACT TRUNCATED AT 400 WORDS) |
| | |
Authors:
|
D N Mastronarde |
Related Documents
:
|
21753194 - Prostaglandin e2 receptors are differentially expressed in subpopulations of granulosa ... 22223104 - Enhanced electrode-reducing rate during the enrichment process in an air-cathode microb... 22130534 - Kaposi's sarcoma associated herpesvirus (kshv) latency associated nuclear antigen (lana... 21647934 - The expression of tousled kinases in cap cell lines and its relation to radiation respo... 22535474 - Differential expression of the 5-ht(3a) and 5-ht (3b) receptor in differentiated ng108-... 827094 - Ultrastructure of aggregates of tumor and normal cells and of mixed aggregates. |
Publication Detail:
|
Type: Journal Article; Research Support, U.S. Gov't, P.H.S. |
Journal Detail:
|
Title: Visual neuroscience Volume: 8 ISSN: 0952-5238 ISO Abbreviation: Vis. Neurosci. Publication Date: 1992 May |
Date Detail:
|
Created Date: 1992-06-24 Completed Date: 1992-06-24 Revised Date: 2007-11-14 |
Medline Journal Info:
|
Nlm Unique ID: 8809466 Medline TA: Vis Neurosci Country: ENGLAND |
Other Details:
|
Languages: eng Pagination: 407-41 Citation Subset: IM |
Affiliation:
|
Department of Molecular, Cellular, and Developmental Biology, University of Colorado, Boulder 80309-0347. |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Animals Cats Electrophysiology Geniculate Bodies / physiology* Interneurons / physiology* Retina / physiology* Visual Cortex / physiology Visual Fields / physiology Visual Pathways / physiology* |
| Grant Support | |
ID/Acronym/Agency:
|
EY-00998/EY/NEI NIH HHS |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: The spontaneous regression of lymphoma in AIDS.
Next Document: Three types of GABA-immunoreactive cone horizontal cells in teleost retina.