Document Detail

Noninvasive recording of His bundle activity with an analog delay device in normal subjects and patients with atrioventricular block.
MedLine Citation:
PMID:  8903999     Owner:  NLM     Status:  MEDLINE    
A simplified and clinically applicable method has been developed for real-time noninvasive recording of the electrical activity of the His bundle in the human heart. A surface electrocardiogram (ECG) was obtained from bipolar precordial leads. The electrical signal within the P-QRS segment of the ECG was amplified with a high gain amplifier and delayed with an analog delay device for QRS-triggered signal averaging. The analog delay device consisted of a bucket brigade device (BBD) with an electrical integrated circuit (IC). After filtering with a band width of 50-300 Hz, the delayed signal was processed by a microcomputer system and the signal-to-noise ratio of the signal was improved by the signal averaging technique. Surface His bundle electrocardiograms (SHE) were measured in normal subjects without conduction disorders and in patients with atrio-ventricular (A-V) block. In the same patients, each SHE was nonsimultaneously compared with an invasive His bundle electrogram (HBE) obtained by the intracardiac catheter technique. The results of this comparison confirmed that the noninvasive method of SHE recording has broad clinical applicability and high utility for the screening of patients with latent A-V block before intracardiac catheterization is performed.
Y Ushiyama; H Okajima; Y Sasaki; M Hasegawa
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Publication Detail:
Type:  Comparative Study; Journal Article    
Journal Detail:
Title:  Heart and vessels     Volume:  10     ISSN:  0910-8327     ISO Abbreviation:  Heart Vessels     Publication Date:  1995  
Date Detail:
Created Date:  1997-02-06     Completed Date:  1997-02-06     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  8511258     Medline TA:  Heart Vessels     Country:  JAPAN    
Other Details:
Languages:  eng     Pagination:  241-8     Citation Subset:  IM    
Department of Physiology, School of Allied Medical Sciences, Shinshu University, Matsumoto, Japan.
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MeSH Terms
Bundle of His / pathology*
Electrocardiography / instrumentation*,  methods
Heart Block / diagnosis*
Sensitivity and Specificity

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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