| Noninvasive recording of His-Purkinje activity in man by ORS-triggered signal averaging. | |
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MedLine Citation:
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PMID: 647894 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Mobile instrumentation and a clinically applicable method have been developed for external His bundle recording. High gain signal amplification (10)(5) filtering (30--300 HZ) and averaging (128 or 256 consecutive cycles) are used. Acquisition of signals arising in the P-R interval is triggered by the patient's QRS signal at the end of that interval. The precordial bipolar electrodiogram is digitized at 5k HZ with 8 bit resolution and transferred to a 1,024 word, 18 bit signal averager. The averaged signal is then displayed on an oscilloscope and photographed. Good correlations were obtained between direct intracardiac and precordial recordings in experimental animals and in humans. Noise level after averaging was below 0.3 microV, and there was good elimination of asynchronous atrial and ectopic ventricular activity. With averaging of 128 or 256 consecutive cycles, the signal attenuation after propagation to the chest wall was in the range 1:2000 to 1:4000 in comparison with the directly recorded His bundle activity deflections. The noninvasive method may be of value in follow-up of acute and chronic disturbances of atrioventricular conduction, as well as in studies of effects of pharmacologic interventions. |
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Authors:
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W J Wajszczuk; M J Stopczyk; M S Moskowitz; R J Zochowski; T Bauld; P L Dabos; M Rubenfire |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Circulation Volume: 58 ISSN: 0009-7322 ISO Abbreviation: Circulation Publication Date: 1978 Jul |
Date Detail:
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Created Date: 1978-07-24 Completed Date: 1978-07-24 Revised Date: 2007-11-15 |
Medline Journal Info:
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Nlm Unique ID: 0147763 Medline TA: Circulation Country: UNITED STATES |
Other Details:
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Languages: eng Pagination: 95-102 Citation Subset: AIM; IM |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Animals Bundle of His / physiology* Dogs Electrocardiography / instrumentation, methods* Evaluation Studies as Topic Heart Conduction System / physiology* Humans Purkinje Fibers / physiology* Time Factors |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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