Document Detail


Noninvasive prediction of hyaline membrane disease: an optimized classification of sonographic placental maturation.
MedLine Citation:
PMID:  3890546     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Accurate prediction of fetal pulmonary maturity by means of a less invasive procedure than amniocentesis would be desirable. Sonographic diagnosis of a Grade III placenta has been reported to be an excellent predictor of fetal lung maturity. The standard classification of placental grading assigns grade according to the most advanced portion of the placenta. Using this classification, we studied 230 patients. In 80 pregnancies with Grade III placenta, three of the neonates developed respiratory distress syndrome. With reclassification of the placentas as immature, (no Grade III areas), intermediate, (only a portion of the placenta being Grade III), or mature, (Grade III placenta throughout), it was found that no neonatal hyaline membrane disease occurred in the 41 pregnancies with mature placentas, whereas 12% of the neonates in the immature group and 8% in the intermediate group developed hyaline membrane disease. These findings suggest that when sonographic examination of the placenta shows both Grade III and non-Grade III sections, there is still a risk for an immature amniotic fluid lecithin/sphingomyelin ratio and neonatal hyaline membrane disease. The placentas should be considered mature only when Grade III changes are present in all sections examined by ultrasound.
Authors:
G M Kazzi; T L Gross; R J Sokol; S N Kazzi
Related Documents :
1138826 - The origin of amnitoic fluid lecithin.
42586 - Active management of high-risk pregnancy.
6639896 - Amniotic fluid phospholipid profile in multiple pregnancy and the effect of zygosity.
12720396 - Changes in physicochemical characteristics and volatile constituents of yellow- and whi...
21194946 - Ultrasound evaluation of fetal movements in pregnancies at risk for severe spinal muscu...
6237186 - Ultrasonographic antenatal diagnosis: will it change the spectrum of neonatal surgery?
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  American journal of obstetrics and gynecology     Volume:  152     ISSN:  0002-9378     ISO Abbreviation:  Am. J. Obstet. Gynecol.     Publication Date:  1985 May 
Date Detail:
Created Date:  1985-07-03     Completed Date:  1985-07-03     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  0370476     Medline TA:  Am J Obstet Gynecol     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  213-9     Citation Subset:  AIM; IM    
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Descriptor/Qualifier:
Amniotic Fluid / metabolism
Female
Fetal Organ Maturity
Gestational Age
Humans
Hyaline Membrane Disease / diagnosis*,  physiopathology
Infant, Newborn
Phospholipids / metabolism
Placenta / pathology,  physiology*
Pregnancy
Risk
Ultrasonography*
Chemical
Reg. No./Substance:
0/Phospholipids

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


Previous Document:  Chorionic villus sampling for first-trimester prenatal diagnosis: Northwestern University program.
Next Document:  Immunoperoxidase localization of chlamydial antigens in acute salpingitis.