Document Detail


Noninvasive monitoring of elevated intramuscular pressure in a model compartment syndrome via quantitative fascial motion.
MedLine Citation:
PMID:  18979529     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Compartment syndromes, conditions of elevated intramuscular pressure (IMP) resulting from trauma or chronic overuse, frequently require invasive IMP monitoring for accurate diagnosis. Our objective was to test a noninvasive ultrasound technique for estimating IMP based on fascial displacement waveforms from arterial blood pressure pulses. IMP was increased in the legs of 23 healthy adult subjects up to 80 mmHg using two blood pressure cuffs covering the region from the knee to the ankle. Receiver operator characteristic curves and recursive partitioning were used to determine the sensitivity and specificity of diagnosing elevated IMP using fascial displacement. For one curve, in which several ultrasonic measurement parameters were used along with subject body mass index and blood pressure, the sensitivity and specificity for diagnosing normal IMP (below 30 mmHg) from elevated IMP (30 mmHg and up) was 0.61 and 0.94, respectively. Recursive partitioning, in which IMP was divided into three ranges (normal <30 mmHg, midrange of 30-40 mmHg, and elevated >or=50 mmHg), resulted in improved diagnostic sensitivity (0.77) with almost no change in specificity (0.93).
Authors:
John E Lynch; John K Lynch; Steven L Cole; Jonathan A Carter; Alan R Hargens
Related Documents :
7435199 - The effect of single dose ergotamine tartrate on peripheral arteries in migraine patien...
7226849 - Determination of blood pressure by indirect methods in dogs given acetylpromazine maleate.
15802289 - Non-invasive pulsatile arterial pressure and stroke volume changes from the human finger.
12706189 - Noninvasive blood pressure measurement in mice using pulsed doppler ultrasound.
17414359 - Wrist tourniquet: the most patient-friendly way of bloodless hand surgery.
660359 - Sphygmomanometry in the pediatric patient.
2433039 - Cardiovascular reflexes mediated by capsaicin sensitive cardiac afferent neurones in th...
1255509 - Secretin-like choleretic effect of prostaglandins e1 and e2 in cats.
9072349 - Endothelin-1 gene expression and vascular hypertrophy in doca-salt hypertension compare...
Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Journal of orthopaedic research : official publication of the Orthopaedic Research Society     Volume:  27     ISSN:  1554-527X     ISO Abbreviation:  J. Orthop. Res.     Publication Date:  2009 Apr 
Date Detail:
Created Date:  2009-03-19     Completed Date:  2009-04-01     Revised Date:  2014-09-15    
Medline Journal Info:
Nlm Unique ID:  8404726     Medline TA:  J Orthop Res     Country:  United States    
Other Details:
Languages:  eng     Pagination:  489-94     Citation Subset:  IM    
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Descriptor/Qualifier:
Adult
Compartment Syndromes / diagnosis,  physiopathology*
Fascia / physiology
Female
Humans
Male
Monitoring, Physiologic
Muscle, Skeletal / physiopathology*
Pressure
Sensitivity and Specificity
Grant Support
ID/Acronym/Agency:
R43 AR053750/AR/NIAMS NIH HHS; R43 AR053750-01/AR/NIAMS NIH HHS
Comments/Corrections

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


Previous Document:  The effects of focal articular defects on cartilage contact mechanics.
Next Document:  Determinants of urinary 8-hydroxy-2'-deoxyguanosine in Chinese children with acute leukemia.