Document Detail

Noninvasive monitoring of elevated intramuscular pressure in a model compartment syndrome via quantitative fascial motion.
MedLine Citation:
PMID:  18979529     Owner:  NLM     Status:  MEDLINE    
Compartment syndromes, conditions of elevated intramuscular pressure (IMP) resulting from trauma or chronic overuse, frequently require invasive IMP monitoring for accurate diagnosis. Our objective was to test a noninvasive ultrasound technique for estimating IMP based on fascial displacement waveforms from arterial blood pressure pulses. IMP was increased in the legs of 23 healthy adult subjects up to 80 mmHg using two blood pressure cuffs covering the region from the knee to the ankle. Receiver operator characteristic curves and recursive partitioning were used to determine the sensitivity and specificity of diagnosing elevated IMP using fascial displacement. For one curve, in which several ultrasonic measurement parameters were used along with subject body mass index and blood pressure, the sensitivity and specificity for diagnosing normal IMP (below 30 mmHg) from elevated IMP (30 mmHg and up) was 0.61 and 0.94, respectively. Recursive partitioning, in which IMP was divided into three ranges (normal <30 mmHg, midrange of 30-40 mmHg, and elevated >or=50 mmHg), resulted in improved diagnostic sensitivity (0.77) with almost no change in specificity (0.93).
John E Lynch; John K Lynch; Steven L Cole; Jonathan A Carter; Alan R Hargens
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Journal of orthopaedic research : official publication of the Orthopaedic Research Society     Volume:  27     ISSN:  1554-527X     ISO Abbreviation:  J. Orthop. Res.     Publication Date:  2009 Apr 
Date Detail:
Created Date:  2009-03-19     Completed Date:  2009-04-01     Revised Date:  2014-09-22    
Medline Journal Info:
Nlm Unique ID:  8404726     Medline TA:  J Orthop Res     Country:  United States    
Other Details:
Languages:  eng     Pagination:  489-94     Citation Subset:  IM    
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MeSH Terms
Compartment Syndromes / diagnosis,  physiopathology*
Fascia / physiology
Monitoring, Physiologic
Muscle, Skeletal / physiopathology*
Sensitivity and Specificity
Grant Support

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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