Document Detail


Noninvasive method for measuring respiratory system compliance during pressure support ventilation.
MedLine Citation:
PMID:  22255169     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
PURPOSE: To date, few methods have been accepted for assessing the respiratory system compliance (C(rs)) in patients under assisted ventilation at the bedside. The aim of this study was to evaluate our adaptive time slice method (ATSM) to continuously calculate the C(rs).
METHODS: One breath is divided into several time periods (slices). For each slice, a compliance value C(i) is calculated. The slice width is adapted according to the confidence interval of C(i). After all C(i) values are obtained and the outliers are eliminated, the C(rs) of this breath is calculated as the mean value of the remainder of C(i)'s. Seven patients with Chronic Obstructive Pulmonary Disease were evaluated during pressure support ventilation. The results are compared with the values calculated with the transdiaphragmatic pressure (P(di)).
RESULTS: 95 ± 4% of the recorded data could be analyzed with ATSM. In 6 patients out of 7, the results delivered with ATSM and with P(di) had similar variation (standard deviation) and accuracy (difference<20%). They were strongly correlated (weighted correlation coefficient = 0.86, p<10(-5)) with a mean difference of 3.22 ml/mbar.
CONCLUSIONS: The ATSM is a robust method and able to provide accurate C(rs) in spontaneously breathing patients during pressure support ventilation noninvasively without extra instrumentation or complicated maneuvers.
Authors:
Zhanqi Zhao; Marcus Eger; Thomas Handzsuj; V Marco Ranieri; Lorenzo Appendini; Cosimo Micelli; Knut Moller
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Conference proceedings : ... Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual Conference     Volume:  2011     ISSN:  1557-170X     ISO Abbreviation:  Conf Proc IEEE Eng Med Biol Soc     Publication Date:  2011  
Date Detail:
Created Date:  2012-01-18     Completed Date:  2012-07-09     Revised Date:  2014-08-21    
Medline Journal Info:
Nlm Unique ID:  101243413     Medline TA:  Conf Proc IEEE Eng Med Biol Soc     Country:  United States    
Other Details:
Languages:  eng     Pagination:  3808-11     Citation Subset:  IM    
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MeSH Terms
Descriptor/Qualifier:
Humans
Lung Compliance
Positive-Pressure Respiration*
Pulmonary Disease, Chronic Obstructive / physiopathology*
Respiratory Mechanics*

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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