| Noninvasive measurement of oxygen tension in the optic nerve head. | |
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MedLine Citation:
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PMID: 10180515 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Understanding the pathophysiology of the optic nerve head (ONH) requires precise knowledge of the oxygenation of this tissue. Previous investigations used methods based on oxygen sensitive microelectrodes to measure the partial pressure of oxygen in the ONH tissue. These microelectrodes are inserted into the eye through the pars plana. New methods are now being developed to measure the intravascular PO2 in the ONH. They are based on the quenching of phosphorescence of a porphyrin dye by oxygen. Although these methods require an intravenous injection of this dye, the eye is left untouched. This article reviews these noninvasive methods. |
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Authors:
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C E Riva |
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Publication Detail:
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Type: Journal Article; Research Support, Non-U.S. Gov't; Review |
Journal Detail:
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Title: Current opinion in ophthalmology Volume: 9 ISSN: 1040-8738 ISO Abbreviation: Curr Opin Ophthalmol Publication Date: 1998 Apr |
Date Detail:
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Created Date: 1998-07-22 Completed Date: 1998-07-22 Revised Date: 2006-11-15 |
Medline Journal Info:
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Nlm Unique ID: 9011108 Medline TA: Curr Opin Ophthalmol Country: UNITED STATES |
Other Details:
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Languages: eng Pagination: 56-60 Citation Subset: T |
Affiliation:
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Institut de Recherche en Ophtalmologie, Sion, Switzerland. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Blood Flow Velocity Humans Image Processing, Computer-Assisted Laser-Doppler Flowmetry Luminescent Measurements Optic Disk / blood supply, metabolism* Oxygen Consumption / physiology* Video Recording |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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