Document Detail


Noninvasive imaging of human skin hemodynamics using a digital red-green-blue camera.
MedLine Citation:
PMID:  21895324     Owner:  NLM     Status:  In-Data-Review    
Abstract/OtherAbstract:
In order to visualize human skin hemodynamics, we investigated a method that is specifically developed for the visualization of concentrations of oxygenated blood, deoxygenated blood, and melanin in skin tissue from digital RGB color images. Images of total blood concentration and oxygen saturation can also be reconstructed from the results of oxygenated and deoxygenated blood. Experiments using tissue-like agar gel phantoms demonstrated the ability of the developed method to quantitatively visualize the transition from an oxygenated blood to a deoxygenated blood in dermis. In vivo imaging of the chromophore concentrations and tissue oxygen saturation in the skin of the human hand are performed for 14 subjects during upper limb occlusion at 50 and 250 mm Hg. The response of the total blood concentration in the skin acquired by this method and forearm volume changes obtained from the conventional strain-gauge plethysmograph were comparable during the upper arm occlusion at pressures of both 50 and 250 mm Hg. The results presented in the present paper indicate the possibility of visualizing the hemodynamics of subsurface skin tissue.
Authors:
Izumi Nishidate; Noriyuki Tanaka; Tatsuya Kawase; Takaaki Maeda; Tomonori Yuasa; Yoshihisa Aizu; Tetsuya Yuasa; Kyuichi Niizeki
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Journal of biomedical optics     Volume:  16     ISSN:  1560-2281     ISO Abbreviation:  J Biomed Opt     Publication Date:  2011 Aug 
Date Detail:
Created Date:  2011-09-07     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9605853     Medline TA:  J Biomed Opt     Country:  United States    
Other Details:
Languages:  eng     Pagination:  086012     Citation Subset:  IM    
Affiliation:
Tokyo University of Agriculture & Technology, Graduate School of Bioapplications and Science Engineering, Koganei, Tokyo 184-8588, JapanKushiro National College of Technology, Department of Mechanical Engineering, Kushiro, Hokkaido 084-0916, JapanMuroran Institute of Technology, College of Design and Manufacturing Technology, Muroran,Hokkaido 050-8588, JapanYamagata University, Graduate School of Biosystem Engineering, Yonezawa, Yamagata 992-8510, Japan.
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