Document Detail


Noninvasive identification of initial site of abnormal ventricular activation by least-square phase analysis of radionuclide cineangiograms.
MedLine Citation:
PMID:  7074809     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Least-square phase analysis (LSPA) of radionuclide cineangiograms demonstrates the sequence of onset of inward ventricular movement noninvasively. To validate the method and explore its ability to identify abnormal initial sites of ventricular activation, LSPA was applied to 14 patients with pacemakers (one with electrodes in two locations) (group 1) and three patients with recurrent ventricular tachycardia (VT) (group 2) who had undergone electrophysiologic endocardial mapping. The segment in which the site of initial ventricular activation was located was correctly identified in 13 of 15 paced studies and in two of three group 2 patients during VT. Pacing increased the duration of spread of onset of inward ventricular movement, and the duration of spread of onset correlated well with the duration of the QRS (r = 0.80). The sequence of onset of inward ventricular movement during VT was similar to the sequence of depolarization in all three group 2 patients. These preliminary results suggest that the sequence of onset of ventricular contraction as depicted by LSPA is a valid representation of the actual contraction sequence and that LSPA or radionuclide cineangiography correctly identifies abnormal sites of initial ventricular activation.
Authors:
D A Turner; P L Von Behren; N T Ruggie; R G Hauser; P Denes; A Ali; J V Messer; E W Fordham; M W Groch
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Circulation     Volume:  65     ISSN:  0009-7322     ISO Abbreviation:  Circulation     Publication Date:  1982 Jun 
Date Detail:
Created Date:  1982-07-22     Completed Date:  1982-07-22     Revised Date:  2007-11-15    
Medline Journal Info:
Nlm Unique ID:  0147763     Medline TA:  Circulation     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  1511-8     Citation Subset:  AIM; IM    
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MeSH Terms
Descriptor/Qualifier:
Arrhythmias, Cardiac / radionuclide imaging*,  therapy
Electrocardiography
Electrophysiology
Heart / radionuclide imaging*
Humans
Myocardial Contraction*
Pacemaker, Artificial
Tachycardia / radionuclide imaging

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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