Document Detail


Noninvasive estimation of cerebral perfusion pressure with transcranial Doppler ultrasonography in traumatic brain injury.
MedLine Citation:
PMID:  22843455     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
AIM: In traumatic brain injury (TBI) patients, to overcome the secondary insults, cerebral perfusion pressure (CPP) oriented therapy is recommended. The study is assigned to estimate CPP values with middle cerebral artery (MCA) flow velocities measured noninvasively using transcranial Doppler ultrasonography (TCD).
MATERIAL AND METHODS: Forty-seven TBI patients were studied. Intracranial pressure (ICP), mean arterial pressure (MAP) and MCA flow velocities of the patients were monitored. Invasive CPP was calculated as the difference between MAP and ICP. The formula : 'MAP x FVd/FVm +14' was used to estimate CPP noninvasively. Correlation of the noninvasive and invasive values were analysed.
RESULTS: The mean values of noninvasive CPP and invasive CPP were 66.10 ± 10.55 mmHg and 65.40 ± 10.03 mmHg respectively. The correlation between noninvasive and invasive CPP measurements was strongly significant (p < 0.001) with a correlation coefficient of r = 0.920.
CONCLUSION: With ICP monitoring systems, CPP is calculated and the therapy is guided according to these values. As it is recognized that brain perfusion can be assessed with TCD waveforms, noninvasive CPP estimation with MCA flow velocities may help to observe the trends in CPP values.
Authors:
Melek Gura; Gokalp Silav; Nejat Isik; Ilhan Elmaci
Related Documents :
8089855 - Developmental pattern of ventricular atrial natriuretic peptide (anp) expression in chr...
21254905 - Impact of new clinical trials on recent guidelines on hypertension management.
8779835 - Natriuretic peptide responses to acute and chronic ventricular pacing in sheep.
7500545 - Changes in the e/a ratio induced by handgrip-exercise are related to changes in the pla...
9761505 - Diurnal blood pressure variation and albuminuria in normotensive patients with insulin-...
2382895 - The effect of hypopnea on low-pressure pulmonary edema.
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Turkish neurosurgery     Volume:  22     ISSN:  1019-5149     ISO Abbreviation:  Turk Neurosurg     Publication Date:  2012  
Date Detail:
Created Date:  2012-07-30     Completed Date:  2012-12-07     Revised Date:  2014-07-31    
Medline Journal Info:
Nlm Unique ID:  9423821     Medline TA:  Turk Neurosurg     Country:  Turkey    
Other Details:
Languages:  eng     Pagination:  411-5     Citation Subset:  IM    
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Descriptor/Qualifier:
Adult
Arterial Pressure
Blood Pressure / physiology*
Brain Hemorrhage, Traumatic / physiopathology,  ultrasonography
Brain Injuries / physiopathology*,  ultrasonography*
Cerebrovascular Circulation / physiology*
Female
Humans
Male
Monitoring, Physiologic
Perfusion
Prospective Studies
Tomography, X-Ray Computed
Ultrasonography, Doppler, Transcranial / methods*

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


Previous Document:  Armored brain in patients with hydrocephalus after shunt surgery: review of the literatures.
Next Document:  Morphological analysis and morphometry of the foramen magnum: an anatomical investigation.