Document Detail

Noninvasive ergonovine maleate provocative testing for coronary artery spasm: the need for routine thallium-201 imaging.
MedLine Citation:
PMID:  6883499     Owner:  NLM     Status:  MEDLINE    
We administered ergonovine and used both electrocardiographic monitoring and thallium-201 [201Tl] imaging to detect reversible ischemia in 100 patients. Patients already established as having coronary artery spasm and those with nonbypassed, proximal, high-grade coronary artery stenosis were excluded. No complication occurred in any patient. The use of thallium imaging in addition to electrocardiographic monitoring resulted in a higher degree of sensitivity than did ECG monitoring alone. Fourteen patients demonstrated evidence of coronary artery spasm as documented by 201Tl imaging but of the 14, significant ECG changes occurred in only 50%, and classic ST segment elevation in 21%. Thus, in carefully selected patients the noninvasive provocation of coronary spasm can be accomplished safely, but ECG monitoring must be combined with thallium-201 imaging to achieve an acceptable degree of sensitivity.
J G Shanes; R J Krone; K Fisher; B Shah; G Eisenkramer; J R Humphrey
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Catheterization and cardiovascular diagnosis     Volume:  9     ISSN:  0098-6569     ISO Abbreviation:  Cathet Cardiovasc Diagn     Publication Date:  1983  
Date Detail:
Created Date:  1983-10-08     Completed Date:  1983-10-08     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  7508512     Medline TA:  Cathet Cardiovasc Diagn     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  271-82     Citation Subset:  IM    
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MeSH Terms
Coronary Disease / diagnosis,  radionuclide imaging
Coronary Vasospasm / complications,  diagnosis*,  radionuclide imaging
Ergonovine / adverse effects,  analogs & derivatives*,  diagnostic use
Middle Aged
Pain / etiology
Radioisotopes / diagnostic use*
Thallium / diagnostic use*
Reg. No./Substance:
0/Radioisotopes; 60-79-7/Ergonovine; 7440-28-0/Thallium

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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