| Noninvasive diagnosis of pulmonary hypertension using heart sound analysis. | |
| | |
MedLine Citation:
|
PMID: 20691967 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
Right-heart catheterization is the most accurate method for measuring pulmonary artery pressure (PAP). It is an expensive, invasive procedure, exposes patients to the risk of infection, and is not suited for long-term monitoring situations. Medical researchers have shown that PAP influences the characteristics of heart sounds. This suggests that heart sound analysis is a potential method for the noninvasive diagnosis of pulmonary hypertension. We describe the development of a prototype system, called PHD (pulmonary hypertension diagnoser), that implements this method. PHD uses patient data with machine learning algorithms to build models of how pulmonary hypertension affects heart sounds. Data from 20 patients were used to build the models and data from another 31 patients were used as a validation set. PHD diagnosed pulmonary hypertension in the validation set with 77% accuracy and 0.78 area under the receiver-operating-characteristic curve. |
| | |
Authors:
|
Aaron Dennis; Andrew D Michaels; Patti Arand; Dan Ventura |
Related Documents
:
|
1781567 - Diastolic mechanics and the origin of the third heart sound. 16018497 - Marine mammals and noise: problems with root mean square sound pressure levels for tran... 12117347 - Downsizing of voice prosthesis diameter in patients with laryngectomy: an in vitro study. 6657637 - Quality of korotkoff sounds: bell vs diaphragm, cubital fossa vs brachial artery. 11561197 - Pressure assessment in intercavernous embedding of bulboperineal urethra for treatment ... 8319997 - Comparative effects of three different potent renin inhibitors in primates. |
Publication Detail:
|
Type: Journal Article Date: 2010-08-06 |
Journal Detail:
|
Title: Computers in biology and medicine Volume: 40 ISSN: 1879-0534 ISO Abbreviation: Comput. Biol. Med. Publication Date: 2010 Sep |
Date Detail:
|
Created Date: 2010-09-13 Completed Date: 2011-01-07 Revised Date: - |
Medline Journal Info:
|
Nlm Unique ID: 1250250 Medline TA: Comput Biol Med Country: United States |
Other Details:
|
Languages: eng Pagination: 758-64 Citation Subset: IM |
Copyright Information:
|
Copyright © 2010 Elsevier Ltd. All rights reserved. |
Affiliation:
|
Department of Computer Science, Brigham Young University, Provo, UT 84602, USA. adennis@byu.edu |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Algorithms Area Under Curve Heart Catheterization / methods Heart Sounds* Humans Hypertension, Pulmonary / diagnosis* ROC Curve Reproducibility of Results |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: [Weight change, cardiometabolic risk and the impact of antidiabetic medications in type 2 diabetic p...
Next Document: Role of the precentral gyrus of the insula in complex articulation.