Document Detail


Noninvasive assessment of cutaneous vascular function in vivo using capillaroscopy, plethysmography and laser-Doppler instruments: its strengths and weaknesses.
MedLine Citation:
PMID:  16687786     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Given that functional abnormalities of the microcirculation are one of the primary abnormalities in cardiovascular disease pathogenesis, various noninvasive clinical tools have been developed recently to assess the microvascular function, particularly at the skin. The common techniques used to assess cutaneous microvascular function in vivo include capillaroscopy, venous occlusion plethysmography, and laser-Doppler instruments (laser-Doppler fluximetry and laser-Doppler imaging). These noninvasive techniques can be used as an early measure of functional abnormalities within the microvascular tree, predominantly in population at high risk for cardiovascular events. This review discusses some underlying application principle of these techniques, including its clinical significance, method reproducibility and limitations.
Authors:
Get Bee Yvonne-Tee; Aida Hanum Ghulam Rasool; Ahmad Sukari Halim; Abdul Rashid Abdul Rahman
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Publication Detail:
Type:  Comparative Study; Journal Article; Review    
Journal Detail:
Title:  Clinical hemorheology and microcirculation     Volume:  34     ISSN:  1386-0291     ISO Abbreviation:  Clin. Hemorheol. Microcirc.     Publication Date:  2006  
Date Detail:
Created Date:  2006-05-11     Completed Date:  2006-09-07     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  9709206     Medline TA:  Clin Hemorheol Microcirc     Country:  Netherlands    
Other Details:
Languages:  eng     Pagination:  457-73     Citation Subset:  IM    
Affiliation:
Department of Pharmacology, School of Medical Sciences, University Sains Malaysia, Kubang Kerian, Kelantan. yvonnetee623@yahoo.com
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MeSH Terms
Descriptor/Qualifier:
Cardiovascular Diseases / physiopathology
Humans
Laser-Doppler Flowmetry* / instrumentation
Microcirculation / abnormalities,  physiopathology
Microscopic Angioscopy*
Plethysmography*
Reproducibility of Results
Risk Factors

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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