| Noninvasive assessment of acute changes in atrial electrophysiology after cardioversion by signal-averaged P-wave electrocardiography. | |
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MedLine Citation:
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PMID: 15679643 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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BACKGROUND: Atrial remodeling secondary to atrial fibrillation (AF) may be important in the arrhythmogenic process. Unfortunately, the study of electrophysiologic remodeling in humans has been limited by the invasive nature of most tests of electrophysiologic characteristics. We sought to determine whether changes in atrial electrophysiology occur acutely (within the first hour) after cardioversion and whether these changes could be detected noninvasively by measuring the signal-averaged P-wave. METHODS: The filtered P-wave duration (FPD) was measured by signal-averaged electrocardiography (ECG) at 20 and 60 minutes after cardioversion in 46 patients with AF, and the difference between the two values was calculated. The root-mean-square voltage of the terminal 40 ms of the signal-averaged P-wave at 20 and 60 minutes and the difference between them were also determined. RESULTS: The FPD at 20 minutes was significantly different from that at 60 minutes (153.0 +/- 19.1 vs 159.7 +/- 24.8 ms; P = 0.02). In a univariate linear regression model, none of the clinical variables studied was significantly associated with the change in FPD. The root-mean-square voltage at 20 minutes was not significantly different from that at 60 minutes (5.8 +/- 3.0 vs 5.5 +/- 2.7; P = 0.14). CONCLUSIONS: We conclude that significant changes in atrial electrophysiology occur within the first hour after cardioversion of AF. These changes can be detected by measuring the FPD. |
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Authors:
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Ahmad A Elesber; Ana Gabriela Rosales; Win-Kuang Shen; Joseph F Malouf; David O Hodge; Naser M Ammash; Krishnaswamy Chandrasekaran; Bernard J Gersh; Stephen C Hammill; Paul A Friedman |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Pacing and clinical electrophysiology : PACE Volume: 28 ISSN: 0147-8389 ISO Abbreviation: Pacing Clin Electrophysiol Publication Date: 2005 Feb |
Date Detail:
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Created Date: 2005-01-31 Completed Date: 2005-06-02 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 7803944 Medline TA: Pacing Clin Electrophysiol Country: United States |
Other Details:
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Languages: eng Pagination: 135-9 Citation Subset: IM |
Affiliation:
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Division of Cardiovascular Diseases, Mayo Clinic, Rochester, Minnesota 55905, USA. |
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| MeSH Terms | |
Descriptor/Qualifier:
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Aged Atrial Fibrillation / physiopathology*, therapy* Electric Countershock* Electrocardiography Female Humans Male Regression Analysis Statistics, Nonparametric Time Factors |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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