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Noninvasive Epileptic Seizure Localization from Stochastic Behavior of Short Duration Interictal High Density Scalp EEG Data.
MedLine Citation:
PMID:  21644027     Owner:  NLM     Status:  Publisher    
Abstract/OtherAbstract:
The stochastic behavior of the phase synchronization index (SI) in different EEG bands was examined for noninvasive localization of the epileptogenic areas from the short duration (30-60 s), seizure-free and spike-free high density (256 channel) scalp EEG data. We also examined the cross-frequency and cross-electrode coupling in different EEG bands. EEG data of four subjects was used. The seizure areas were localized with subdural recordings with an 8×8 grid electrode array. It was found that the stochastic behavior of the SI in low gamma band (30-50 Hz) was higher in epileptogenic areas. The beta (12-30 Hz) band also showed similar tendencies. The stochastic behavior in theta (3-7 Hz) band was depressed in the seizure area while it was widespread in large areas over the scalp in the alpha (7-12 Hz) band. The stochastic behavior of the cross-frequency and cross-electrode couplings in theta-gamma, alpha-gamma and beta-gamma bands were decreased in the seizure areas for all four subjects. These findings suggest that it is possible to localize the epileptogenic areas from the short duration seizure-free and spike-free high density scalp EEG data.
Authors:
Ceon Ramon; Mark D Holmes
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Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2011-6-5
Journal Detail:
Title:  Brain topography     Volume:  -     ISSN:  1573-6792     ISO Abbreviation:  -     Publication Date:  2011 Jun 
Date Detail:
Created Date:  2011-6-6     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8903034     Medline TA:  Brain Topogr     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Affiliation:
Departments of Electrical Engineering, University of Washington, Campus Box 352500, Seattle, WA, 98115, USA, ceon@u.washington.edu.
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