| Noninfectious anterior uveitis in patients infected with human T-lymphotropic virus type I. | |
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MedLine Citation:
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PMID: 2576286 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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A consecutive series of 34 patients with HTLV-I-associated myelopathy (HAM), a neurological disease associated with human T-lymphotropic virus type I (HTLV-I), were studied with reference to endogenous ocular disorders. These patients were examined at the Kagoshima University Hospital between 1986 and 1988. Five of the 34 HAM patients showed noninfectious, granulomatous anterior uveitis responding to corticosteroid therapy and/or retinal microvascular changes such as isolated cotton-wool spots; one of the patients had recurrent uveitis. Additionally, twelve of 30 patients who had been infected with HTLV-I but remained healthy systemically had ocular manifestations similar to those in HAM patients were included in this study. The ocular lesions in these patients were not explained by any established disorders that manifest uveitis or retinal microangiopathy. Some of the HTLV-I-seropositive patients with ocular disorders showed antibodies against HTLV-I in the aqueous humor. This might have resulted from diffusion of serum antibodies through a damaged blood-aqueous barrier or local synthesis of antibodies. The HTLV-I infection might be primarily responsible for a certain form of endogenous anterior uveitis that has remained hitherto etiologically undefined. |
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Authors:
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K Nakao; N Ohba; M Matsumoto |
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Publication Detail:
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Type: Case Reports; Journal Article |
Journal Detail:
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Title: Japanese journal of ophthalmology Volume: 33 ISSN: 0021-5155 ISO Abbreviation: Jpn. J. Ophthalmol. Publication Date: 1989 |
Date Detail:
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Created Date: 1990-04-11 Completed Date: 1990-04-11 Revised Date: 2004-11-17 |
Medline Journal Info:
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Nlm Unique ID: 0044652 Medline TA: Jpn J Ophthalmol Country: JAPAN |
Other Details:
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Languages: eng Pagination: 472-81 Citation Subset: IM; X |
Affiliation:
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Department of Ophthalmology, Kagoshima University Faculty of Medicine, Japan. |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Adult Aged Albumins / metabolism Aqueous Humor / immunology Deltaretrovirus Antibodies / blood, cerebrospinal fluid Female Humans Immunoglobulin G / metabolism Male Middle Aged Paraparesis, Tropical Spastic / complications*, immunology Retinal Diseases / etiology* Uveitis, Anterior / etiology* Visual Acuity |
| Chemical | |
Reg. No./Substance:
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0/Albumins; 0/Deltaretrovirus Antibodies; 0/Immunoglobulin G |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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