Document Detail

Nonheartbeating cadaveric organ donation.
MedLine Citation:
PMID:  7944668     Owner:  NLM     Status:  MEDLINE    
OBJECTIVE: The authors evaluated the potential use of nonheartbeating (NHB) cadaver donors as an additional source to the current supply of brain-dead cadaver donors. SUMMARY BACKGROUND DATA: The numbers of cadaveric donors has not increased significantly during the last 5 years, despite a rising need for transplantable organs. Any improvement in cadaveric organ procurement will depend on the use of previously unrecognized potential donors. METHODS: During a 2-year period, 24 kidneys were retrieved from 12 NHB donors. Nineteen kidneys were transplanted. RESULTS: These kidneys sustained a mean warm ischemia time of 26 minutes (range 20-35 min). A mean lowest creatinine level of 2.0 mg/dL, (range 1.1-3.0 mg/dL), the rate of postoperative dialysis (22%), and a 1-year graft survival rate of 76% for kidneys from NHB-donated kidneys compare favorably to expected results achieved nationally from brain-dead cadaveric donors. CONCLUSIONS: Nonheartbeating donor kidneys can yield acceptable graft function and be of no disadvantage to recipients of cadaver transplants.
M S Orloff; A I Reed; E Erturk; R A Kruk; S A Paprocki; S C Cimbalo; G J Cerilli
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Annals of surgery     Volume:  220     ISSN:  0003-4932     ISO Abbreviation:  Ann. Surg.     Publication Date:  1994 Oct 
Date Detail:
Created Date:  1994-11-10     Completed Date:  1994-11-10     Revised Date:  2009-11-18    
Medline Journal Info:
Nlm Unique ID:  0372354     Medline TA:  Ann Surg     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  578-83; discussion 583-5     Citation Subset:  AIM; IM    
Department of Surgery, University of Rochester Medical Center, New York 14642-8410.
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MeSH Terms
Brain Death
Graft Survival / physiology
Kidney Failure, Chronic / mortality,  physiopathology,  surgery*
Kidney Transplantation* / methods,  physiology
Postoperative Care
Renal Dialysis
Survival Rate
Tissue Donors* / supply & distribution
Tissue and Organ Procurement / methods*

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