Document Detail

Nonexudative diarrhea after gold salt therapy: case report and review of the literature.
MedLine Citation:
PMID:  6401389     Owner:  NLM     Status:  MEDLINE    
A case of fulminant watery diarrhea after therapy with 485 mg of gold thioglucose in a 78-yr-old woman suffering from rheumatoid arthritis is presented. Evaluation failed to reveal evidence of infection, malabsorption, or mucosal inflammation. Treatment, after stopping therapy, was supportive over several months and the patient recovered completely. A comparison with other presentations of gold induced diarrhea is made through a review of all known cases reported in the literature. Although these cases have many points in common, it is apparent that there is a spectrum of disease from fatal hemorrhagic diarrhea to nonexudative diarrhea. Any diarrhea in a patient receiving gold salt therapy must be thoroughly investigated before continuing therapy.
J Nagler; S A Paget
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  The American journal of gastroenterology     Volume:  78     ISSN:  0002-9270     ISO Abbreviation:  Am. J. Gastroenterol.     Publication Date:  1983 Jan 
Date Detail:
Created Date:  1983-02-14     Completed Date:  1983-02-14     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  0421030     Medline TA:  Am J Gastroenterol     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  12-4     Citation Subset:  IM    
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MeSH Terms
Arthritis, Rheumatoid / drug therapy
Aurothioglucose / adverse effects*,  therapeutic use
Diarrhea / chemically induced*,  therapy
Gold / adverse effects*
Reg. No./Substance:
12192-57-3/Aurothioglucose; 7440-57-5/Gold

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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