| Nonerythropoietic properties of erythropoietin: implication for tissue protection. | |
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MedLine Citation:
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PMID: 22011619 Owner: NLM Status: In-Data-Review |
Abstract/OtherAbstract:
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Erythropoietin (EPO) is used at present in clinical practice to stimulate red cell production. However, a number of reports have emerged suggesting the presence of nonerythropoietic properties for EPO. Chief among them is its ability to confer protection against acute tissue injury. In this report, we briefly review the role of EPO in tissue protection and provide examples of tissue protection using cisplatin-induced kidney injury model. Also provided is a brief description of potential pathways through which EPO may be mediating this effect. |
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Authors:
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Dhanesh B Rathod; Abdulla K Salahudeen |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Journal of investigative medicine : the official publication of the American Federation for Clinical Research Volume: 59 ISSN: 1708-8267 ISO Abbreviation: J. Investig. Med. Publication Date: 2011 Oct |
Date Detail:
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Created Date: 2011-10-20 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 9501229 Medline TA: J Investig Med Country: Canada |
Other Details:
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Languages: eng Pagination: 1083-5 Citation Subset: IM |
Affiliation:
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From the Nephrology Section, Department of General Internal Medicine, The University of Texas M. D. Anderson Cancer Center, Houston, TX. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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