| Nonenhanced methods for lower-extremity MRA: a phantom study examining the effects of stenosis and pathologic flow waveforms at 1.5T. | |
| | |
MedLine Citation:
|
PMID: 21274982 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
PURPOSE: To evaluate the signal properties of 2D time of flight (TOF), quiescent-interval single-shot (QISS), ECG-gated 3D fast spin-echo (FBI), and ungated 3D fast spin-echo ghost (Ghost) magnetic resonance angiography (MRA) over a range of flow velocities in a pulsatile flow phantom with a 50% diameter stenosis at 1.5T. MATERIALS AND METHODS: Blood-mimicking fluid was pumped at eight peak flow velocities through a stenotic region in triphasic and monophasic waveforms. Vascular signal proximal, within, and distal to the stenosis was measured from the source images of the four MRA methods. Coronal maximum intensity projection images were used to compare image quality. RESULTS: TOF and QISS signal trends were similar, but QISS exhibited the most consistent signal across velocities. At high velocities (≥ 42.4 cm/s), TOF showed poststenotic signal loss that was not observed with QISS. FBI and Ghost signals peaked at low velocities (3.9-9.7 cm/s) without flow compensation and at high velocities (≥ 64.6 cm/s) with flow compensation. CONCLUSION: FBI and Ghost demonstrated dependence on blood flow velocity and flow compensation. TOF was sensitive to flow artifacts at high velocities. QISS proved most robust for accurately depicting the normal lumen and stenosis under a wide range of flow conditions. Monophasic and triphasic flow did not appreciably affect the signal performance of any method. |
| | |
Authors:
|
Erik J Offerman; Philip A Hodnett; Robert R Edelman; Ioannis Koktzoglou |
Publication Detail:
|
Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't |
Journal Detail:
|
Title: Journal of magnetic resonance imaging : JMRI Volume: 33 ISSN: 1522-2586 ISO Abbreviation: J Magn Reson Imaging Publication Date: 2011 Feb |
Date Detail:
|
Created Date: 2011-01-28 Completed Date: 2011-05-13 Revised Date: 2011-11-14 |
Medline Journal Info:
|
Nlm Unique ID: 9105850 Medline TA: J Magn Reson Imaging Country: United States |
Other Details:
|
Languages: eng Pagination: 401-8 Citation Subset: IM |
Copyright Information:
|
Copyright © 2011 Wiley-Liss, Inc. |
Affiliation:
|
Department of Radiology, NorthShore University HealthSystem, Evanston, Illinois 60201, USA. EOfferman@northshore.org |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Arterial Occlusive Diseases
/
diagnosis* Blood Flow Velocity Contrast Media Humans Image Enhancement Image Interpretation, Computer-Assisted / methods* Lower Extremity / blood supply*, pathology*, physiopathology Magnetic Resonance Angiography / instrumentation, methods* Peripheral Arterial Disease / diagnosis* Phantoms, Imaging Reproducibility of Results Sensitivity and Specificity |
| Grant Support | |
ID/Acronym/Agency:
|
R01 HL096916-02/HL/NHLBI NIH HHS; R01HL096916/HL/NHLBI NIH HHS |
| Chemical | |
Reg. No./Substance:
|
0/Contrast Media |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Fast spin-echo triple echo dixon: Initial clinical experience with a novel pulse sequence for simult...
Next Document: Evaluation of possible drug-drug interaction between gadoxetic acid and erythromycin as an inhibitor...