| Nonenhanced extracranial carotid MR angiography using arterial spin labeling: Improved performance with pseudocontinuous tagging. | |
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MedLine Citation:
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PMID: 21780230 Owner: NLM Status: In-Data-Review |
Abstract/OtherAbstract:
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PURPOSE: To compare pulsed arterial spin labeling (PASL) and pseudocontinuous arterial spin labeling (PCASL) for nonenhanced extracranial carotid MR angiography (MRA). MATERIALS AND METHODS: Parametric signal equations for PASL and PCASL MRA were formulated and compared. Volunteer imaging (n = 7) at 1.5 Tesla was performed to compare the methods over a broad range of repetition and labeling times. Empirical results were compared with theoretical predictions. The feasibility of the optimal method was investigated in patients (n = 2) with sonographically documented carotid artery disease. RESULTS: In volunteers, PCASL provided significantly improved signal than PASL (range: 32-255% improvement; P < 0.01), and better supported the use of long labeling times and short repetition times. Excellent agreement between theory and experiment was found (intraclass correlation coefficient = 0.966; P < 0.001). PCASL provided excellent depiction of the carotid arteries in initial patient studies. CONCLUSION: Compared with pulsed tagging, pseudocontinuous tagging provides improved performance for nonenhanced extracranial carotid MRA and warrants further clinical investigation. J. Magn. Reson. Imaging 2011;. © 2011 Wiley-Liss, Inc. |
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Authors:
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Ioannis Koktzoglou; Navyash Gupta; Robert R Edelman |
Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Journal of magnetic resonance imaging : JMRI Volume: 34 ISSN: 1522-2586 ISO Abbreviation: J Magn Reson Imaging Publication Date: 2011 Aug |
Date Detail:
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Created Date: 2011-07-22 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 9105850 Medline TA: J Magn Reson Imaging Country: United States |
Other Details:
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Languages: eng Pagination: 384-94 Citation Subset: IM |
Copyright Information:
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Copyright © 2011 Wiley-Liss, Inc. |
Affiliation:
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Department of Radiology, NorthShore University HealthSystem, Evanston, Illinois, USA; The University of Chicago Pritzker School of Medicine, Chicago, Illinois, USA. ikoktzoglou@northshore.org. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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