| Nonendometrioid endometrial carcinomas. | |
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MedLine Citation:
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PMID: 21309259 Owner: NLM Status: In-Process |
Abstract/OtherAbstract:
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Clinicopathologic studies support a classification of endometrial carcinoma into two main categories (type I and type II). Type I cancers consist of endometrioid and mucinous carcinomas, with the former being the most common, whereas serous and clear cell carcinomas are the so-called "prototype" of type II cancers. Nonendometrioid carcinomas account for approximately 10% of endometrial carcinomas and differ from endometrioid carcinomas in terms of patient demographics, morphologic features, and biological behavior. Molecular studies have provided further insights into the differing alterations involved in the development and progression of these tumors. This review summarizes the characteristic clinical, morphologic, immunophenotypic, and molecular features of the various subtypes of nonendometrioid carcinomas and also highlights relevant conditions (both nonneoplastic and neoplastic) that should be considered in the differential diagnosis of these tumors. |
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Authors:
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Diana Lim; Esther Oliva |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Seminars in diagnostic pathology Volume: 27 ISSN: 0740-2570 ISO Abbreviation: Semin Diagn Pathol Publication Date: 2010 Nov |
Date Detail:
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Created Date: 2011-02-11 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 8502262 Medline TA: Semin Diagn Pathol Country: United States |
Other Details:
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Languages: eng Pagination: 241-60 Citation Subset: IM |
Affiliation:
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Pathology Department, Massachusetts General Hospital, Boston, Massachusetts 02114, USA. |
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Descriptor/Qualifier:
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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