| Nonendemic adult T-cell leukemia/lymphoma in the United States: report of two cases and review of the literature. | |
| | |
MedLine Citation:
|
PMID: 2981466 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
Adult T-cell leukemia/lymphoma (ATLL) is a recently described distinct clinicopathologic entity characterized by a leukemic or lymphomatous proliferation of hyperlobulated peripheral T-cells, which is usually widespread at presentation and is associated with infection by a type C retrovirus. ATLL rarely is described outside of endemic regions, which include southwestern Japan, the Caribbean region, and the southeastern United States. The authors report the clinical, pathologic, and immunologic features of two cases of nonendemic ATLL that occurred in patients from the midwest United States. One patient was a 16-year-old white girl from rural Iowa, and the other was a 46-year-old white man from rural Minnesota. The features of 13 other probable nonendemic ATLL cases from the United States were compiled and reviewed. In the United States, nonendemic ATLL occurred in widespread geographic locations, affected mostly white people, and was characterized by an aggressive course with generalized adenopathy, blood and bone marrow involvement, and hepatosplenomegaly at presentation. Skin involvement was present in one-fourth of the patients. Hypercalcemia was rare. Although antibodies to type C retrovirus were detected in three of the five patients tested, the available data is not sufficient to establish a conclusive association between nonendemic ATLL and type C retrovirus infection. |
| | |
Authors:
|
K Foucar; T J Carroll; R Tannous; L Peterson; J A Goeken; S Binion; J Gajl-Peczalska; M E Kadin; W M Yokoyama |
Related Documents
:
|
18634466 - The rabies situation in far east asia. 11596716 - Measles: how many hospitalised cases are we missing? 20943026 - Amblyomma aureolatum (acari: ixodidae) parasitizing margay (leopardus wiedii) in rio gr... 8627926 - Avian tick paralysis caused by ixodes brunneus in the southeastern united states. 2327446 - Postpartum cardiovascular complications after bromocriptine and cocaine use. 3704706 - Haemophilus paraphrophilus endocarditis. |
Publication Detail:
|
Type: Case Reports; Journal Article |
Journal Detail:
|
Title: American journal of clinical pathology Volume: 83 ISSN: 0002-9173 ISO Abbreviation: Am. J. Clin. Pathol. Publication Date: 1985 Jan |
Date Detail:
|
Created Date: 1985-02-04 Completed Date: 1985-02-04 Revised Date: 2004-11-17 |
Medline Journal Info:
|
Nlm Unique ID: 0370470 Medline TA: Am J Clin Pathol Country: UNITED STATES |
Other Details:
|
Languages: eng Pagination: 18-26 Citation Subset: AIM; IM; X |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Adolescent Bone Marrow / pathology Deltaretrovirus Female Humans Leukemia / epidemiology, pathology Leukocyte Count Liver / pathology Lymph Nodes / pathology Male Middle Aged Retroviridae Infections / complications Spleen / pathology United States |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: New positive inotropic drugs for the treatment of congestive heart failure.
Next Document: Reproducibility of the French-American-British classification of acute leukemia: the Southwest Oncol...