| Noncontrast-enhanced peripheral MRA: Technical optimization of flow-spoiled fresh blood imaging for screening peripheral arterial diseases. | |
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MedLine Citation:
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PMID: 20872867 Owner: NLM Status: In-Data-Review |
Abstract/OtherAbstract:
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Flow-spoiled fresh blood imaging, a noncontrast peripheral MR angiography technique, allows the depiction of the entire tree of peripheral arteries by utilizing the signal difference between systolic- and diastolic-triggered data. The image quality of the technique relies on selecting the right triggering delay times and flow-dependent read-out spoiler gradient pulses. ECG triggering delays were verified using manual subtraction and automated software. The read-out spoiler gradients pulses were optimized on volunteers before utilizing the flow-spoiled fresh blood imaging technique to screen for peripheral arterial disease. Thirteen consecutive patients with suspected peripheral arterial disease underwent both flow-spoiled fresh blood imaging and 16-detector-row computed tomography angiography examinations. A total of 23 segments were evaluated in the arterial vascular system. Using computed tomography angiography as the reference standard, 56 diseased segments were detected with 22 nonsignificant stenoses (<50%) and 34 significant stenoses, 15 of which were totally occluded. Flow-spoiled fresh blood imaging had a sensitivity of 97%, a specificity of 96%, an accuracy of 96%, a positive predictive value of 88%, and a negative predictive value of 99%. With such a high negative predictive value, flow-spoiled fresh blood imaging has the potential to become the safest noninvasive screening tool for peripheral arterial disease, especially for patients with impaired renal function. Magn Reson Med, 2011. © 2010 Wiley-Liss, Inc. |
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Authors:
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Katsumi Nakamura; Mitsue Miyazaki; Kiyomi Kuroki; Akiyoshi Yamamoto; Akihiro Hiramine; Faiza Admiraal-Behloul |
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Publication Detail:
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Type: Journal Article Date: 2010-09-24 |
Journal Detail:
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Title: Magnetic resonance in medicine : official journal of the Society of Magnetic Resonance in Medicine / Society of Magnetic Resonance in Medicine Volume: 65 ISSN: 1522-2594 ISO Abbreviation: Magn Reson Med Publication Date: 2011 Feb |
Date Detail:
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Created Date: 2011-01-25 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 8505245 Medline TA: Magn Reson Med Country: United States |
Other Details:
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Languages: eng Pagination: 595-602 Citation Subset: IM |
Copyright Information:
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Copyright © 2010 Wiley-Liss, Inc. |
Affiliation:
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Department of Radiology, Tobata Kyoritsu Hospital, Kitakyushu, Fukuoka, Japan. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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