Document Detail

Noncompaction and endocarditis in suspected mitochondrial disorder.
MedLine Citation:
PMID:  17303269     Owner:  NLM     Status:  MEDLINE    
OBJECTIVES: To report the echocardiographic and autopsy findings of left ventricular hypertrabeculation (LVHT), also known as noncompaction, in a patient with central and peripheral nervous system disease, who died shortly after diagnosing noncompaction. CASE REPORT: In a 75 year old woman with cognitive decline, Parkinson syndrome, stroke-like-episodes, basal ganglia calcification, neuromuscular disorder, cataract, diabetes, anemia, arterial hypertension, recurrent heart failure, left anterior hemiblock, and right bundle branch block, acute heart failure developed during treatment of a suspected urosepsis. Transthoracic echocardiography revealed severely reduced fractional shortening, valvular vegetations, and LVHT. Endocarditis was suspected. She died shortly afterwards from renal failure and ventricular fibrillation. Endocarditis and LVHT were confirmed at autopsy. CONCLUSIONS: This case shows that endocarditis may occur together with LVHT and central and peripheral nervous system disease indicative of a mitochondrial disorder. Whether LVHT predisposes for endocarditis remains speculative.
Josef Finsterer; Claudia Stöllberger; Hans Feichtinger
Related Documents :
2480059 - Congenital complete heart block in patients without anatomic cardiac defects.
3346929 - Transient heart block associated with head trauma.
6202309 - Patterns of ventricular contraction in patients with conduction abnormality studied by ...
7120649 - Electrophysiological delineation of the specialized conduction system under cardiotomy ...
6204289 - His bundle recordings using epicardial pacing wires: a new technique.
1693199 - Persistent functional atrioventricular block in two patients with prolonged qt interval...
9841599 - Effect of pravastatin on cardiovascular events in older patients with myocardial infarc...
16880329 - Inhibition of urokinase-type plasminogen activator or matrix metalloproteinases prevent...
9342369 - Restoration of beta-adrenergic signaling in failing cardiac ventricular myocytes via ad...
Publication Detail:
Type:  Case Reports; Letter     Date:  2007-02-14
Journal Detail:
Title:  International journal of cardiology     Volume:  123     ISSN:  1874-1754     ISO Abbreviation:  Int. J. Cardiol.     Publication Date:  2008 Jan 
Date Detail:
Created Date:  2007-12-25     Completed Date:  2008-01-18     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8200291     Medline TA:  Int J Cardiol     Country:  Netherlands    
Other Details:
Languages:  eng     Pagination:  e45-7     Citation Subset:  IM    
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Central Nervous System Diseases / complications,  pathology*,  ultrasonography
Echocardiography, Transesophageal
Endocarditis / complications,  pathology*,  ultrasonography
Fatal Outcome
Heart Failure / complications,  pathology*,  ultrasonography
Hypertrophy, Left Ventricular / complications,  pathology*,  ultrasonography
Mitochondria / pathology*,  ultrasonography

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

Previous Document:  Acquired coronary cameral fistula--a report of two cases.
Next Document:  Sensitivity analysis to identify key-parameters in modelling the spread of bovine viral diarrhoea vi...