| Nonclassic adrenal hyperplasia due to 21-hydroxylase deficiency. | |
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MedLine Citation:
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PMID: 3302893 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Nonclassic adrenal hyperplasia due to 21-hydroxylase deficiency (21-OHD) is an autosomal recessive disorder distinguished from classic 21-OHD by clinical and hormonal criteria. It is most often described as a disorder of adrenal steroidogenesis with onset of virilization in late childhood, peripubertally or postpubertally. An overview of adrenal steroidogenesis is presented elsewhere in this publication. It is the aim of this article to focus on the clinical and hormonal manifestations of the disorder, with discussion of the current methods of diagnosis and management. Recent advances in classic and molecular genetics will follow. |
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Authors:
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S Drucker; M I New |
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Publication Detail:
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Type: Journal Article; Research Support, U.S. Gov't, P.H.S.; Review |
Journal Detail:
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Title: Pediatric clinics of North America Volume: 34 ISSN: 0031-3955 ISO Abbreviation: Pediatr. Clin. North Am. Publication Date: 1987 Aug |
Date Detail:
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Created Date: 1987-09-02 Completed Date: 1987-09-02 Revised Date: 2007-11-14 |
Medline Journal Info:
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Nlm Unique ID: 0401126 Medline TA: Pediatr Clin North Am Country: UNITED STATES |
Other Details:
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Languages: eng Pagination: 1067-81 Citation Subset: AIM; IM |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adrenal Hyperplasia, Congenital*
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etiology,
genetics Female Glucocorticoids / therapeutic use HLA Antigens / genetics Heterozygote Detection Humans Pedigree Steroid Hydroxylases / deficiency* |
| Grant Support | |
ID/Acronym/Agency:
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R01 HD 00072/HD/NICHD NIH HHS; R01 HL 17749/HL/NHLBI NIH HHS; RR47/RR/NCRR NIH HHS |
| Chemical | |
Reg. No./Substance:
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0/Glucocorticoids; 0/HLA Antigens; EC 1.14.-/Steroid Hydroxylases |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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