| Noncirrhotic portal hypertension associated with Didanosine: a case report and literature review. | |
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MedLine Citation:
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PMID: 22274160 Owner: NLM Status: In-Data-Review |
Abstract/OtherAbstract:
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Noncirrhotic portal hypertension (NCPH) has recently been reported as a liver complication in human immunodeficiency virus (HIV)-infected patients and has been found to be associated with exposure to didanosine. Here, we describe the case of an HIV-infected patient with portal hypertension who initially presented with massive ascites and portal vein thrombosis. The patient's HIV-1 infection was well-controlled with highly active antiretroviral therapy (lamivudine/didanosine plus nevirapine) for 3 years since its diagnosis in 2007. He had no history of alcoholism, drug abuse, or liver diseases. An extensive work-up for other possible causes of liver disease was performed, but the results were inconclusive. In addition to reporting this case, we have reviewed the literature on didanosine-related NCPH and analyzed the findings of 61 similar previously reported cases. |
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Authors:
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Hui-Min Chang; Hung-Chin Tsai; Susan Shin-Jung Lee; Shue-Ren Wann; Yao-Shen Chen |
Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Japanese journal of infectious diseases Volume: 65 ISSN: 1344-6304 ISO Abbreviation: Jpn. J. Infect. Dis. Publication Date: 2012 Jan |
Date Detail:
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Created Date: 2012-01-25 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 100893704 Medline TA: Jpn J Infect Dis Country: Japan |
Other Details:
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Languages: eng Pagination: 61-5 Citation Subset: IM |
Affiliation:
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Department of Pharmacy, Kaohsiung Veterans General Hospital, Kaohsiung, Taiwan. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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