Document Detail

Noncervicofacial atypical mycobacterial lymphadenitis in childhood.
MedLine Citation:
PMID:  11528601     Owner:  NLM     Status:  MEDLINE    
BACKGROUND/PURPOSE: Atypical mycobacterial (AM) lymphadenitis is common in children but rarely occurs outside the cervicofacial region. The authors report their experience in the diagnosis and management of noncervicofacial AM lymphadenitis. METHODS: A retrospective review was conducted of cases diagnosed at our institution between January 1976 and December 1999, based on positive culture of atypical mycobacteria or consistent histology with supportive skin testing. RESULTS: Thirty-seven patients were identified over the 23-year review period. The median age was 4.3 years (range, 8 months to 13 years and 5 months), with 19 boys and 17 girls. The median duration of symptoms was 4 weeks, and the most commonly affected sites were the inguinal region (n = 17), axilla (n = 8), and lower limb (n = 6). Preceding local trauma was described in 10 patients and a viral illness in 4. Laboratory culture for atypical mycobacteria was positive in 22, and skin testing suggestive in 21 and equivocal in 2. Treatment was by excision in 28 and drainage with or without curettage in 9. At a median follow-up of 19.7 months, disease had recurred in 4 patients, none of whom had been treated initially by excision. CONCLUSIONS: Atypical mycobacterial infection is an uncommon cause of noncervicofacial lymphadenitis in children. It typically presents with a 4-week history of painless regional lymphadenopathy that may follow penetrating trauma. If untreated, the overlying skin becomes involved with a violaceous discoloration, and ulceration may occur. Definitive treatment involves complete surgical excision, preferably before suppuration extending beyond the involved lymph nodes.
A J Holland; J Holland; H C Martin; G Cummins; C Cooke-Yarborough; D T Cass
Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Journal of pediatric surgery     Volume:  36     ISSN:  0022-3468     ISO Abbreviation:  J. Pediatr. Surg.     Publication Date:  2001 Sep 
Date Detail:
Created Date:  2001-08-30     Completed Date:  2001-12-04     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  0052631     Medline TA:  J Pediatr Surg     Country:  United States    
Other Details:
Languages:  eng     Pagination:  1337-40     Citation Subset:  IM    
Copyright Information:
Copyright 2001 by W.B. Saunders Company.
Department of Academic Surgery, The Children's Hospital at Westmead, Royal Alexandra Hospital for Children, The University of Sydney, New South Wales, Australia.
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MeSH Terms
Age Distribution
Antitubercular Agents / administration & dosage
Child, Preschool
Combined Modality Therapy
Drainage / methods
Follow-Up Studies
Lymphadenitis / microbiology,  therapy*
Mycobacteria, Atypical / isolation & purification
Mycobacterium Infections, Atypical / diagnosis*,  therapy*
Retrospective Studies
Risk Assessment
Sex Distribution
Treatment Outcome
Reg. No./Substance:
0/Antitubercular Agents

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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