Document Detail

Noncardiac chest pain of esophageal origin in patients with and without coronary artery disease.
MedLine Citation:
PMID:  15966206     Owner:  NLM     Status:  MEDLINE    
BACKGROUND/AIMS: Non-cardiac chest pain is a frequent finding in patients admitted to emergency departments, and it has been shown that many of these patients may have an esophageal cause for their pain. However, little data are available on patients primarily referred to the cardiology unit, and especially those with coronary artery disease. The purpose of this study was to assess the role of esophageal dysfunction in chest pain patients with and without coronary artery disease. METHODOLOGY: Eighty-one patients referred from a cardiology unit for chest pain and no myocardial infarction entered the study. Sixty-one patients had no evidence of coronary artery disease, whereas 20 had coronary artery disease with chest pain at rest. After the cardiological evaluation, the patients underwent esophageal function testing by means of upper endoscopy, manometry, and 24-hour pH-monitoring. RESULTS: Overall, 10% of patients (2.5% in the coronary artery disease group) had evidence of endoscopic esophagitis, 46% of esophageal motor disorders (12% in the coronary artery disease group), and 10% abnormal pH-monitoring (1% in the coronary artery disease group). CONCLUSIONS: We report that the esophagus might be responsible for non-cardiac chest pain in patients with and without coronary artery disease. In our experience, esophageal motor disorders, and not an increased acid reflux, are the abnormalities most commonly found in these patients.
Edda Battaglia; Gabrio Bassotti; Giuseppina Buonafede; Anna Maria Serra; Luca Dughera; Fulvio Orzan; Roberta Casoni; Fabio Chistolini; Antonio Morelli; Giorgio Emanuelli
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Hepato-gastroenterology     Volume:  52     ISSN:  0172-6390     ISO Abbreviation:  Hepatogastroenterology     Publication Date:    2005 May-Jun
Date Detail:
Created Date:  2005-06-21     Completed Date:  2005-12-15     Revised Date:  2007-11-15    
Medline Journal Info:
Nlm Unique ID:  8007849     Medline TA:  Hepatogastroenterology     Country:  Greece    
Other Details:
Languages:  eng     Pagination:  792-5     Citation Subset:  IM    
Servizio di Endoscopia e Motilità Intestinale, Cattedra di Medicina Interna, Dipartimento di Fisiopatologia Clinica, Università di Torino, Italy.
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MeSH Terms
Chest Pain / epidemiology,  etiology*
Coronary Artery Disease / diagnosis*,  epidemiology
Coronary Care Units / statistics & numerical data
Cross-Sectional Studies
Diagnosis, Differential
Esophageal Motility Disorders / diagnosis*,  epidemiology
Esophagitis / diagnosis*,  epidemiology
Middle Aged

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