Document Detail

Nonapical tako-tsubo cardiomyopathy associated with coronary slow flow: a case report and review of the literature.
MedLine Citation:
PMID:  19816866     Owner:  NLM     Status:  MEDLINE    
The exact pathophysiology of tako-tsubo cardiomyopathy (TTC) is unclear. A nonapical form of TTC precipitated by emotional stress is presented. Findings on 12 lead ECG and coronary angiogram are discussed. The role of specialized investigations such as cardiac MRI and tissue Doppler imaging are reviewed. We then examine the probable molecular explanations for this condition and suggest a probable molecular mechanism based on animal studies. Future therapeutic options are also briefly discussed.
Unni Krishnan; Amanda Zacharzewski; Matthias Schmitt
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Publication Detail:
Type:  Case Reports; Journal Article; Review    
Journal Detail:
Title:  Clinical cardiology     Volume:  32     ISSN:  1932-8737     ISO Abbreviation:  Clin Cardiol     Publication Date:  2009 Nov 
Date Detail:
Created Date:  2009-11-30     Completed Date:  2010-02-04     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  7903272     Medline TA:  Clin Cardiol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  E63-6     Citation Subset:  IM    
Department of Cardiovascular Sciences, Glenfield Hospital, University Hospitals of Leicester NHS Trust, Groby Road, Leicester LE3 9QP, United Kingdom.
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MeSH Terms
Coronary Angiography
Coronary Circulation*
Echocardiography, Doppler
Magnetic Resonance Imaging
Middle Aged
No-Reflow Phenomenon / diagnosis,  etiology*,  physiopathology
Predictive Value of Tests
Stress, Psychological / complications*,  physiopathology
Takotsubo Cardiomyopathy / diagnosis,  etiology*,  physiopathology

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