Document Detail

Nonalcoholic fatty liver disease as a component of the metabolic syndrome.
MedLine Citation:
PMID:  18417046     Owner:  NLM     Status:  MEDLINE    
Nonalcoholic fatty liver disease (NAFLD) is an important cause of liver-related morbidity and mortality. The association between NAFLD and the metabolic syndrome is well established: the presence of the metabolic syndrome signifies advanced histology in NAFLD patients. Emerging data indicate that patients with NAFLD have a significantly higher prevalence of cardiovascular disease. This article reviews the definitions of the two syndromes, their association, and the cardiovascular risk conferred by both when they occur separately and together. This review also discusses management options for the syndromes, including treating the individual components of the metabolic syndrome in NAFLD patients.
Mouen A Khashab; Suthat Liangpunsakul; Naga Chalasani
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Publication Detail:
Type:  Journal Article; Review    
Journal Detail:
Title:  Current gastroenterology reports     Volume:  10     ISSN:  1534-312X     ISO Abbreviation:  Curr Gastroenterol Rep     Publication Date:  2008 Feb 
Date Detail:
Created Date:  2008-04-17     Completed Date:  2008-09-15     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  100888896     Medline TA:  Curr Gastroenterol Rep     Country:  United States    
Other Details:
Languages:  eng     Pagination:  73-80     Citation Subset:  IM    
Indiana University School of Medicine, RG 4100, 1050 Wishard Boulevard, Indianapolis, IN 46202, USA.
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MeSH Terms
Cardiovascular Diseases / complications
Fatty Liver / complications*,  epidemiology
Metabolic Syndrome X / complications*,  epidemiology,  therapy
Obesity / complications,  therapy

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