Document Detail


Non-transplant surgical therapy options of heart failure.
MedLine Citation:
PMID:  25420501     Owner:  NLM     Status:  In-Data-Review    
Abstract/OtherAbstract:
Congestive heart failure (CHF) results from damage to the myocardium and has a broad etiology ranging from ischemic to non-ischemic etiology. It is one of the leading causes of cardiovascular morbidity and mortality and carries a 5-year mortality of 50%, estimated by WHO to represent 30% of deaths in the United States. Costs related to the care of patients with CHF have increased substantially over the past 2 decades partly owing to increased frequency of hospitalization, implantation of costly novel devices and, as the disease progresses, consideration for heart transplantation, mechanical circulatory support, and end-of-life care. CHF progression is accompanied by changes within the myocardium, collectively referred to as left ventricular remodeling, which can be categorized into changes in the cardiomyocytes and changes that occur in the volume and composition of the extracellular matrix. Since remodeling in heart failure is progressive and detrimental, the majority of treatment strategies are aimed at stopping or possibly reversing this process. Some successful methods include medical management, long-term or destination mechanical circulatory support, cardiac resychronization therapy, and biventricular pacemakers. During the last few decades, the management of heart failure has evolved tremendously with the introduction of new therapies and assist devices. Advances in mechanical support, left ventricular assist devices (LVADs), and total artificial heart have significantly reduced mortality in patients awaiting transplantation. This manuscript is an overview of non-transplant surgical options in the management of CHF.
Authors:
S Neragi-Miandoab
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Minerva cardioangiologica     Volume:  62     ISSN:  1827-1618     ISO Abbreviation:  Minerva Cardioangiol     Publication Date:  2014 Dec 
Date Detail:
Created Date:  2014-11-25     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0400725     Medline TA:  Minerva Cardioangiol     Country:  Italy    
Other Details:
Languages:  eng     Pagination:  481-96     Citation Subset:  IM    
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Descriptor/Qualifier:

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


Previous Document:  Impact of reperfusion strategy on outcomes in very elderly patients with acute myocardial infarction...
Next Document:  Difficulties at work and work motivation of ulcerative colitis suffers.