Document Detail

Non-toxic antifouling activity of polymeric 3-alkylpyridinium salts from the Mediterranean sponge Reniera sarai (Pulitzer-Finali).
MedLine Citation:
PMID:  14618688     Owner:  NLM     Status:  MEDLINE    
The antifouling activity and toxicity of polymeric 3-alkylpyridinium salts (poly-APS) isolated from the Mediterranean sponge Reniera sarai were studied. The activity of these natural products was compared to that of zinc and copper complexes of pyrithione, two non-persistent booster biocides successfully used in current antifouling coatings. Larvae of Balanus amphitrite (cyprids and nauplii) were used to monitor settlement inhibition and the extent to which inhibition was due to toxicity. The microalga Tetraselmis suecica and larvae of the mussel Mytilus galloprovincialis were used in toxicity bioassays. Compared to the booster biocides, poly-APS were less effective at inhibiting cyprid settlement, but their effects were non toxic and reversible, with very low toxicity against the organisms used in the toxicity bioassays. Although encouraging, these results are not enough to warrant the use of poly-APS as a potential commercial antifoulant. They however justify possible future efforts to chemically synthesize poly-APS analogues for further tests.
Marco Faimali; Kristina Sepcić; Tom Turk; Sebastiano Geraci
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Publication Detail:
Type:  Comparative Study; Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Biofouling     Volume:  19     ISSN:  0892-7014     ISO Abbreviation:  Biofouling     Publication Date:  2003 Feb 
Date Detail:
Created Date:  2003-11-17     Completed Date:  2003-11-28     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  9200331     Medline TA:  Biofouling     Country:  England    
Other Details:
Languages:  eng     Pagination:  47-56     Citation Subset:  IM    
Consiglio Nazionale delle Ricerche, Istituto per la Corrosione Marina dei Metalli, Via De Marini 6, 16149 Genova, Italy.
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MeSH Terms
Algae, Green / drug effects*,  growth & development
Biological Assay
Bivalvia / drug effects*,  physiology
Larva / drug effects,  physiology
Mediterranean Sea
Polymers / chemistry,  toxicity*
Porifera / chemistry*
Pyridinium Compounds / chemistry,  toxicity*
Swimming / physiology
Thoracica / drug effects*,  physiology
Toxicity Tests
Reg. No./Substance:
0/Polymers; 0/Pyridinium Compounds; 0/poly-APS

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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