| Non-suture end-to-end anastomoses between polytetrafluoroethylene graft and vessels for blood access. | |
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MedLine Citation:
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PMID: 10230263 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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BACKGROUND: Non-suture end-to-end anastomoses between polytetrafluoroethylene grafts and blood vessels were achieved using absorbable cuff material in experimental and clinical studies. The cuff was made of a synthetic biodegradable material, a lactic-glycolic acid copolymer, similar in composition to conventional absorbable surgical sutures. METHODS: In the experimental study, vascular anastomoses for prosthetic interposition of the infrarenal aorta in rabbits were created using the cuff method. Six months after surgery, the cuff anastomoses sites were examined angiographically and microscopically and found to be patent and smooth without neointimal hyperplasia. RESULTS: The cuff layer had been completely absorbed. The clinical application used a similar technique and involved the creation of forearm bridge graft fistula in twelve patients for hemodialysis. In eight patients, Doppler fistula flow rate ranged from 167 ml/min to 392 ml/min. Ten of the twelve patients continued dialysis uneventfully. The one-year patency rate was 78% (7/9). The longest patency period was 920 days and the graft access continued to maintain sufficient blood flow for hemodialysis. CONCLUSIONS: This absorbable cuff material is therefore well suited for the construction of prosthetic vascular end-to-end anastomoses. |
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Authors:
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K Sumimoto; I Tanaka; Y Fukuda; N Haruta; K Dohi; H Ito; T Tsuchiya; Y Ikada |
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Publication Detail:
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Type: Case Reports; Clinical Trial; Journal Article |
Journal Detail:
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Title: Panminerva medica Volume: 41 ISSN: 0031-0808 ISO Abbreviation: Panminerva Med Publication Date: 1999 Mar |
Date Detail:
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Created Date: 1999-06-02 Completed Date: 1999-06-02 Revised Date: 2004-11-17 |
Medline Journal Info:
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Nlm Unique ID: 0421110 Medline TA: Panminerva Med Country: ITALY |
Other Details:
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Languages: eng Pagination: 72-7 Citation Subset: IM |
Affiliation:
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First Department of Surgery, Hiroshima Prefectural Hospital, Japan. |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Aged Anastomosis, Surgical / methods* Animals Blood Vessel Prosthesis Implantation* Female Humans Middle Aged Polytetrafluoroethylene* Rabbits Sutures Vascular Surgical Procedures* |
| Chemical | |
Reg. No./Substance:
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9002-84-0/Polytetrafluoroethylene |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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