Document Detail

Non-surgical treatment of splenic cyst, using with installation of minocycline chloride.
MedLine Citation:
PMID:  9127967     Owner:  NLM     Status:  MEDLINE    
Solitary splenic cysts are relatively rare and usually asymptomatic. However, large ones sometimes show clinical manifestations. Non-surgical treatment of a solitary splenic cyst by instillation of minocycline chloride is described. Minocycline chloride was instilled into the splenic cyst through a pig-tail catheter indwelt under ultrasonographic guidance. Low concentration of minocycline chloride (200 mg diluted in 100 ml of saline) was not effective to reduce discharge from the splenic cyst. Discharged volume was markedly reduced after the instillation of high concentration of minocycline chloride (2000 mg diluted in 100 ml of saline). Eight weeks after this treatment, fluid discharge ceased. After 1 year, there was no findings of enlargement of the cyst. Ultrasonogram guided percutaneous instillation of minocycline chloride is a safe, easy, and useful procedure for treatment of a solitary and benign splenic cyst.
K Shimanuki; M Satake
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Fukushima journal of medical science     Volume:  42     ISSN:  0016-2590     ISO Abbreviation:  Fukushima J Med Sci     Publication Date:  1996 Dec 
Date Detail:
Created Date:  1997-05-14     Completed Date:  1997-05-14     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  0374626     Medline TA:  Fukushima J Med Sci     Country:  JAPAN    
Other Details:
Languages:  eng     Pagination:  23-30     Citation Subset:  IM    
Department of Surgery, Fukushima Municipal Minami Aizu Hospital, Japan.
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MeSH Terms
Aged, 80 and over
Cysts / drug therapy*,  ultrasonography
Minocycline / therapeutic use*
Splenic Diseases / drug therapy*,  ultrasonography
Reg. No./Substance:

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