Document Detail


Non-specific reactions caused by diluents containing glycerol in nasal and bronchial challenge tests.
MedLine Citation:
PMID:  556187     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Sixty-one patients hospitalized because of asthma and/or allergic rhinitis were given nasal and bronchial challenge tests with diluents containing glycerol. 62% of the patients with rhinitis and 37% of those with asthma gave positive reactions. Glycerol should therefore not be used in allergen extracts which are meant for challenge tests. The non-specific effect of glycerol seems to be cumulative with increasing dose.
Authors:
T Haahtela; A Lahdensuo
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Clinical allergy     Volume:  9     ISSN:  0009-9090     ISO Abbreviation:  Clin. Allergy     Publication Date:  1979 May 
Date Detail:
Created Date:  1979-10-26     Completed Date:  1979-10-26     Revised Date:  2005-11-17    
Medline Journal Info:
Nlm Unique ID:  0311172     Medline TA:  Clin Allergy     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  225-7     Citation Subset:  IM    
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MeSH Terms
Descriptor/Qualifier:
Administration, Intranasal
Adult
Asthma / chemically induced*
Forced Expiratory Volume
Glycerol / adverse effects*
Humans
Middle Aged
Respiratory Function Tests
Rhinitis, Allergic, Seasonal / chemically induced*
Chemical
Reg. No./Substance:
56-81-5/Glycerol

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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