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Non-pharmacological Interventions in Hypertension: A Community-based Cross-over Randomized Controlled Trial.
MedLine Citation:
PMID:  22090672     Owner:  NLM     Status:  PubMed-not-MEDLINE    
Abstract/OtherAbstract:
BACKGROUND: Hypertension is the most prevalent non-communicable disease causing significant morbidity/mortality through cardiovascular, cerebrovascular, and renal complications.
OBJECTIVES: This community-based study tested the efficacy of non-pharmacological interventions in preventing/controlling hypertension.
MATERIALS AND METHODS: This is a cross-over randomized controlled trial (RCT) of the earlier RCT (2007) of non-pharmacological interventions in hypertension, conducted in the urban service area of our Institute. The subjects, prehypertensive and hypertensive young adults (98 subjects: 25, 23, 25, 25 in four groups) were randomly allotted into a group that he/she had not belonged to in the earlier RCT: Control (New Group I), Physical Exercise (NG II)-brisk walking for 50 to 60 minutes, three to four days/week, Salt Intake Reduction (NG III) to at least half of their previous intake, Yoga (NG IV) for 30 to 45 minutes/day, five days/week. Blood pressure was measured before and after eight weeks of intervention. Analysis was by ANOVA with a Games-Howell post hoc test.
RESULTS: Ninety-four participants (25, 23, 21, 25) completed the study. All three intervention groups showed significant reduction in BP (SBP/DBP mmHg: 5.3/6.0 in NG II, 2.5/2.0 in NG III, and 2.3/2.4 in NG IV, respectively), while the Control Group showed no significant difference. Persistence of significant reduction in BP in the three intervention groups after cross-over confirmed the biological plausibility of these non-pharmacological interventions. This study reconfirmed that physical exercise was more effective than Salt Reduction or Yoga. Salt Reduction, and Yoga were equally effective.
CONCLUSION: Physical exercise, salt intake reduction, and yoga are effective non-pharmacological methods for reducing blood pressure in young pre-hypertensive and hypertensive adults.
Authors:
Hema Subramanian; M Bala Soudarssanane; R Jayalakshmy; D Thiruselvakumar; D Navasakthi; Ajit Sahai; Lg Saptharishi
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Indian journal of community medicine : official publication of Indian Association of Preventive & Social Medicine     Volume:  36     ISSN:  1998-3581     ISO Abbreviation:  Indian J Community Med     Publication Date:  2011 Jul 
Date Detail:
Created Date:  2011-11-17     Completed Date:  2011-11-23     Revised Date:  2013-05-29    
Medline Journal Info:
Nlm Unique ID:  9315574     Medline TA:  Indian J Community Med     Country:  India    
Other Details:
Languages:  eng     Pagination:  191-6     Citation Subset:  -    
Affiliation:
Department of Preventive and Social Medicine, Jawaharlal Institute of Postgraduate Medical Education and Research, Puducherry, India.
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