Document Detail


Non-nucleolar transcription complexes of rat liver as revealed by spreading isolated nuclei.
MedLine Citation:
PMID:  536385     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Miller's technique was applied to isolated nuclei of rat liver. Both the usual nucleolar and non-nucleolar transcription complexes were visualized. In addition, an unusual type of putative non-ribosomal transcription unit was revealed. It was charcaterized by a high density of the lateral ribonucleoprotein (RNP) fibrils. Although these particular units exhibited a regular increase of fibril lengths, the length of the transcript-covered deoxyribonucleoprotein (DNP) fibres and the morphological aspect of the RNP fibrils distinguished them from the nucleolar 'Christmas-tree'-like figures. The linear and granular configuration of the transcripts and the absence of terminal knobs made them similar to non-nucleolar nascent RNP fibrils.
Authors:
F Harper; F Puvion-Dutilleul
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Journal of cell science     Volume:  40     ISSN:  0021-9533     ISO Abbreviation:  J. Cell. Sci.     Publication Date:  1979 Dec 
Date Detail:
Created Date:  1980-05-23     Completed Date:  1980-05-23     Revised Date:  2003-11-14    
Medline Journal Info:
Nlm Unique ID:  0052457     Medline TA:  J Cell Sci     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  181-92     Citation Subset:  IM    
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MeSH Terms
Descriptor/Qualifier:
Animals
Cell Nucleus / ultrastructure*
DNA
Deoxyribonucleoproteins*
Liver / ultrastructure*
Male
Microscopy, Electron
Nucleic Acid Conformation
Nucleoproteins*
Rats
Transcription, Genetic*
Chemical
Reg. No./Substance:
0/Deoxyribonucleoproteins; 0/Nucleoproteins; 9007-49-2/DNA

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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