Document Detail

Non-nicotine pharmacotherapies for smoking cessation.
MedLine Citation:
PMID:  16011894     Owner:  NLM     Status:  MEDLINE    
International chronic obstructive pulmonary disease guidelines recommend that smokers be strongly advised to quit, and should be offered help in doing so. The most effective smoking-cessation interventions combine behavioural support with pharmacotherapies. For smokers who do not wish to use nicotine replacement treatments, bupropion is a safe and effective non-nicotine alternative first-line treatment. Nortriptyline and clonidine have demonstrated efficacy in aiding smoking cessation, but are regarded as second-line therapies. A number of other non-nicotine treatments show promise, but more data are required before these can be recommended in assisting smokers to stop.
H McRobbie; M Lee; Z Juniper
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Publication Detail:
Type:  Journal Article; Review    
Journal Detail:
Title:  Respiratory medicine     Volume:  99     ISSN:  0954-6111     ISO Abbreviation:  Respir Med     Publication Date:  2005 Oct 
Date Detail:
Created Date:  2005-09-05     Completed Date:  2006-03-06     Revised Date:  2007-11-15    
Medline Journal Info:
Nlm Unique ID:  8908438     Medline TA:  Respir Med     Country:  England    
Other Details:
Languages:  eng     Pagination:  1203-12     Citation Subset:  IM    
Tobacco Dependence Research and Treatment Centre, Barts and The London, Queen Mary's School of Medicine and Dentistry, Turner Street, London E1 2AD, UK.
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MeSH Terms
Adrenergic alpha-Agonists / therapeutic use
Antidepressive Agents, Tricyclic / therapeutic use
Bupropion / therapeutic use
Clonidine / therapeutic use
Dopamine Uptake Inhibitors / therapeutic use
Nortriptyline / therapeutic use
Randomized Controlled Trials as Topic
Smoking / drug therapy*,  prevention & control
Smoking Cessation / methods*
Reg. No./Substance:
0/Adrenergic alpha-Agonists; 0/Antidepressive Agents, Tricyclic; 0/Dopamine Uptake Inhibitors; 34841-39-9/Bupropion; 4205-90-7/Clonidine; 72-69-5/Nortriptyline

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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