Document Detail


Non-motor symptoms in atypical and secondary parkinsonism: the PRIAMO study.
MedLine Citation:
PMID:  19669613     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
The PRIAMO study is a cross-sectional longitudinal observational study aimed at describing epidemiology and evolution of non-motor symptoms (NMS) in patients with different forms of parkinsonism recruited in 55 Italian centres and evaluated over 24 months. In this paper, we are reporting prevalence and clinical characteristics of NMS in patients with atypical and secondary parkinsonism. Out of 1307 consecutive patients with a diagnosis of parkinsonism, 83 patients had vascular parkinsonism (VP), 34 had multiple system atrophy (MSA), 30 had progressive supranuclear palsy (PSP), 14 had dementia with Lewy bodies (DLB) and 11 had corticobasal degeneration (CBD). MSA and DLB had the highest number of NMS domains and symptoms, respectively. Gastrointestinal symptoms, pain, urinary problems and postural instability due to orthostatic hypotension were most frequent in MSA. Sleep disturbances were also common with a prevalence of approximately 70% in all diagnostic groups but CBD (36%). Psychiatric symptoms and attention and memory impairment were frequently observed in all diagnoses but were most prevalent among DLB patients, whereas the prevalence of skin and respiratory disorders was rather low in all forms, ranging between 10 and 30%. Atypical parkinsonism patients also reported a low QoL, with no significant differences among the different forms, whereas PD and VP patients had a better QoL.
Authors:
Carlo Colosimo; Letterio Morgante; Angelo Antonini; Paolo Barone; Tania P Avarello; Edo Bottacchi; Antonino Cannas; Maria Gabriella Ceravolo; Roberto Ceravolo; Giulio Cicarelli; Rosa M Gaglio; Luisa Giglia; Francesco Iemolo; Michela Manfredi; Giuseppe Meco; Alessandra Nicoletti; Massimo Pederzoli; Alfredo Petrone; Antonio Pisani; Francesco E Pontieri; Rocco Quatrale; Silvia Ramat; Rossana Scala; Giampiero Volpe; Salvatore Zappulla; Anna Rita Bentivoglio; Fabrizio Stocchi; Giorgio Trianni; Paolo Del Dotto; Lucia Simoni; Roberto Marconi;
Related Documents :
18952243 - Creativity in parkinson's disease as a function of right versus left hemibody onset.
6981783 - Vestibular dysfunction in parkinson disease.
16649723 - Use and side-effect profile of spironolactone in a private cardiologist's practice.
Publication Detail:
Type:  Journal Article; Multicenter Study; Research Support, Non-U.S. Gov't     Date:  2009-08-09
Journal Detail:
Title:  Journal of neurology     Volume:  257     ISSN:  1432-1459     ISO Abbreviation:  J. Neurol.     Publication Date:  2010 Jan 
Date Detail:
Created Date:  2009-12-24     Completed Date:  2010-03-09     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0423161     Medline TA:  J Neurol     Country:  Germany    
Other Details:
Languages:  eng     Pagination:  5-14     Citation Subset:  IM    
Affiliation:
Dipartimento di Scienze Neurologiche, Sapienza Universit? di Roma, Rome, Italy. carlo.colosimo@uniroma1.it
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Descriptor/Qualifier:
Aged
Cross-Sectional Studies
Female
Humans
Italy / epidemiology
Lewy Body Disease / epidemiology
Longitudinal Studies
Male
Middle Aged
Multiple System Atrophy / epidemiology
Neurodegenerative Diseases / epidemiology
Parkinson Disease, Secondary / epidemiology*
Parkinsonian Disorders / epidemiology*
Prevalence
Supranuclear Palsy, Progressive / epidemiology
Investigator
Investigator/Affiliation:
Angelo Antonini / ; Paolo Barone / ; Carlo Colosimo / ; Roberto Marconi / ; Letterio Morgante / ; D Benincasa / ; S Biguzzi / ; M Braga / ; M Capecci / ; N Caravona / ; G D'Asta / ; F A De Falco / ; D De Gaspari / ; G Pezzoli / ; M Di Giovanni / ; G Floris / ; S Gallerini / ; L Grasso / ; G Gurgone / ; L Kiferle / ; S Meoni / ; F Morgante / ; R Savica / ; V Moschella / ; F Pepe / ; V Petretta / ; M G Randisi / ; M Romeno / ; G Santangelo / ; M Ianniciell / ; V Sorbello / ; G Fabbrini / ; A Berardelli / ; A Guidubaldi / ; R Muoio / ; V Toni / ; C Logi / ; G Ciacci / ; M Ulivelli / ; M Perini / ; S Lanfranchi / ; S Griffini / ; B Troianiello / ; M Baratti / ; S Amidei / ; D Consoli / ; M Iellamo / ; T Cuomo / ; A Scaglioni / ; D Medici / ; G Abbruzzese / ; G Di Brigida / ; G A Cocco / ; V Agnetti / ; G Cossu / ; M Deriu / ; M Abrignani / ; C Modica / ; G Albani / ; E Milan / ; P Martinelli / ; C Scaglione / ; M Mucchiut / ; S Zanini / ; F Pennisi / ; P Soliveri / ; A Albanese / ; L Bartolomei / ; R L'erario / ; L Capus / ; L Ferigo / ; R Marano / ; V Nastasi / ; R Luciano / ; L Maiello / ; P Simone / ; D Fogli / ; L Lopiano / ; M Pesare / ; G Nordera / ; E Pilleri / ; T Scaravilli / ; E Giaccaglini / ; C Alesi / ; Tania Corbetta / ; Arina Dumitriu / ; Simona Sgarbi / ; Andrea Rapisarda / ; Sara Rizzoli / ; Lucia Simoni / ; Luca Zanoli / ; Alessandra Manfredi /

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


Previous Document:  Anthropometric characterization of spleen in children.
Next Document:  The "human influenza receptor" Neu5Ac alpha2,6Gal is expressed among different taxa of wild birds.