Document Detail

Non-invasive ventilation in acute cardiogenic pulmonary oedema.
MedLine Citation:
PMID:  16210459     Owner:  NLM     Status:  MEDLINE    
Non-invasive ventilation (NIV) is the delivery of assisted mechanical ventilation to the lungs, without the use of an invasive endotracheal airway. NIV has revolutionised the management of patients with various forms of respiratory failure. It has decreased the need for invasive mechanical ventilation and its attendant complications. Cardiogenic pulmonary oedema (CPO) is a common medical emergency, and NIV has been shown to improve both physiological and clinical outcomes. From the data presented herein, it is clear that there is sufficiently high level evidence to favour the use of continuous positive airway pressure (CPAP), and that the use of CPAP in patients with CPO decreases intubation rate and improves survival (number needed to treat seven and eight respectively). However, there is insufficient evidence to recommend the use of bilevel positive airway pressure (BiPAP), probably the exception being patients with hypercapnic CPO. More trials are required to conclusively define the role of BiPAP in CPO.
R Agarwal; A N Aggarwal; D Gupta; S K Jindal
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Publication Detail:
Type:  Journal Article; Review    
Journal Detail:
Title:  Postgraduate medical journal     Volume:  81     ISSN:  1469-0756     ISO Abbreviation:  Postgrad Med J     Publication Date:  2005 Oct 
Date Detail:
Created Date:  2005-10-07     Completed Date:  2006-03-08     Revised Date:  2009-11-18    
Medline Journal Info:
Nlm Unique ID:  0234135     Medline TA:  Postgrad Med J     Country:  England    
Other Details:
Languages:  eng     Pagination:  637-43     Citation Subset:  IM    
Department of Pulmonary Medicine, Postgraduate Institute of Medical Education and Research, Chandigarh, India.
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MeSH Terms
Acute Disease
Continuous Positive Airway Pressure / methods*
Decision Making
Evidence-Based Medicine
Intermittent Positive-Pressure Ventilation / methods*
Pulmonary Edema / therapy*
Pulmonary Gas Exchange
Randomized Controlled Trials as Topic

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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