| Non-invasive studies of peripheral vascular compliance using a non-occluding photoplethysmographic method. | |
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MedLine Citation:
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PMID: 10367467 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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A non-invasive technique is implemented to measure a peripheral vascular compliance index Cindex, using an infrared photoplethysmographic waveform as an indicator of intravascular volume change and a continuous blood pressure monitor to measure the blood pressure during each heart-beat. The non-linear behaviour of Cindex with pressure and the effect of age on Cindex are studied in 62 males (15-73 years). Repeatability tests and the effect of ice-water exposure of a portion of a limb are studied in 10 and 14 subjects, respectively. For each individual, Cindex measurements are taken at discrete values of local mean arterial pressure (Pmean), and a Cindex against Pmean plot is obtained. There is a statistically significant difference (p < 0.05) in Cindex for the lower values of Pmean (60-100 mmHg) between two age groups formed (15-52 and 58-73 years). The cold-pressor test (CPT) shows a 68% median decrease in Cindex, with an inter-quartile range of 60-77%, in a matter of seconds. The results suggest that Cindex may be a useful noninvasive indicator of peripheral vascular compliance in humans. |
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Authors:
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E A López-Beltrán; P L Blackshear; S M Finkelstein; J N Cohn |
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Publication Detail:
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Type: Journal Article; Research Support, U.S. Gov't, P.H.S. |
Journal Detail:
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Title: Medical & biological engineering & computing Volume: 36 ISSN: 0140-0118 ISO Abbreviation: Med Biol Eng Comput Publication Date: 1998 Nov |
Date Detail:
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Created Date: 1999-06-28 Completed Date: 1999-06-28 Revised Date: 2007-11-14 |
Medline Journal Info:
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Nlm Unique ID: 7704869 Medline TA: Med Biol Eng Comput Country: ENGLAND |
Other Details:
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Languages: eng Pagination: 748-53 Citation Subset: IM |
Affiliation:
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Biomedical Engineering Program, University of Minnesota, USA. ebeltran@depeca.alcala.es |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adolescent Adult Aged Aging / physiology Blood Pressure Compliance Fingers / blood supply* Humans Male Middle Aged Photoplethysmography / methods* |
| Grant Support | |
ID/Acronym/Agency:
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F31 GM 09586-06/GM/NIGMS NIH HHS |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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