Document Detail

Non-invasive prediction of fluid responsiveness in infants using pleth variability index.
MedLine Citation:
PMID:  21539529     Owner:  NLM     Status:  Publisher    
This prospective study assessed whether respiratory variations in velocity time integral, peak blood flow velocity and non-invasive pleth variability index are useful measurements in infants undergoing congenital heart surgery and determined threshold values that may help guide fluid administration. In 27 infants receiving mechanical ventilation, of mean (SD) weight 10.4 (6.3) kg, 13 increased their stroke volume index ≥ 15% following a fluid challenge and 14 did not. The best area under the receiver operating characteristic curve was for the echocardiographic-derived variables respiratory variation in blood peak flow velocity (area under the ROC curve = 0.92; p = 0.0002) and respiratory variation of the velocity time integral (area under the ROC curve = 0.84; p = 0.002). The pleth variability index also predicted fluid responsiveness (area under the ROC curve = 0.79; p = 0.01), in contrast to heart rate (area under the ROC curve = 0.53; p = 0.75) and central venous pressure (area under the ROC curve = 0.57; p = 0.52).
J Renner; O Broch; M Gruenewald; J Scheewe; H Francksen; O Jung; M Steinfath; B Bein
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Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2011-5-3
Journal Detail:
Title:  Anaesthesia     Volume:  -     ISSN:  1365-2044     ISO Abbreviation:  -     Publication Date:  2011 May 
Date Detail:
Created Date:  2011-5-4     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0370524     Medline TA:  Anaesthesia     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Copyright Information:
© 2011 The Authors. Anaesthesia © 2011 The Association of Anaesthetists of Great Britain and Ireland.
 Associate Professor  Staff Member  Professor of Anaesthesiology and Chair  Professor of Anaesthesiology, Department of Anaesthesiology and Intensive Care Medicine  Associate Professor, Department of Cardiovascular Surgery  Staff Member, Department of Paediatric Cardiology, University Hospital of Schleswig-Holstein, Campus Kiel, Germany.
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