| Non-invasive and high-sensitivity scanning detection of magnetic nanoparticles in animals using high-T(c) scanning superconducting-quantum-interference-device biosusceptometry. | |
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MedLine Citation:
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PMID: 21895259 Owner: NLM Status: In-Data-Review |
Abstract/OtherAbstract:
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Although magnetic nanoparticles (MNPs) have been widely applied to animals in biomedicine, MNPs within animals should be examined in real time, in vivo, and without bio-damaged possibility to evaluate whether the bio-function of MNPs is valid or to further controls the biomedicinal process because of accompanying complex problems such as MNPs distribution and MNPs biodegradation. The non-invasive and high-sensitivity scanning detection of MNPs in animals using ac susceptometry based on a high-T(c) superconducting quantum interference device (SQUID) is presented. The non-invasive results and biopsy results show good agreement, and two gold-standard biomedicine methods, Prussian blue stain and inductively coupled plasma, prove the magnetic results. This confirms that the future clinical diagnosis of bio-functional MNPs could be operated by using scanning SQUID biosusceptometry as conveniently as an ultrasonic probe. |
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Authors:
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J J Chieh; C Y Hong |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: The Review of scientific instruments Volume: 82 ISSN: 1089-7623 ISO Abbreviation: Rev Sci Instrum Publication Date: 2011 Aug |
Date Detail:
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Created Date: 2011-09-07 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 0405571 Medline TA: Rev Sci Instrum Country: United States |
Other Details:
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Languages: eng Pagination: 084301 Citation Subset: IM |
Affiliation:
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Institute of Electro-Optical Science and Technology, National Taiwan Normal University, Taipei 116, TaiwanGraduate Institute of Biomedical Engineering, National Chung Hsing University, Taichung 402, Taiwan. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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