| Non-invasive diagnostic and prognostic evaluation of liver cirrhosis and portal hypertension. | |
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MedLine Citation:
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PMID: 22045398 Owner: NLM Status: In-Data-Review |
Abstract/OtherAbstract:
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Cirrhosis is the final stage of most of chronic liver diseases, and is almost invariably complicated by portal hypertension, which is the most important cause of morbidity and mortality in these patients. This review will focus on the non-invasive methods currently used in clinical practice for diagnosing liver cirrhosis and portal hypertension. The first-line techniques include physical examination, laboratory parameters, transient elastography and Doppler-US. More sophisticated imaging methods which are less commonly employed are CT scan and MRI, and new technologies which are currently under evaluation are MR elastography and acoustic radiation force imaging (ARFI). Even if none of them can replace the invasive measurement of hepatic venous pressure gradient and the endoscopic screening of gastroesophageal varices, they notably facilitate the clinical management of patients with cirrhosis and portal hypertension, and provide valuable prognostic information. |
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Authors:
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Annalisa Berzigotti; Eyal Ashkenazi; Enric Reverter; Juan G Abraldes; Jaime Bosch |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Disease markers Volume: 31 ISSN: 1875-8630 ISO Abbreviation: Dis. Markers Publication Date: 2011 Jan |
Date Detail:
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Created Date: 2011-11-02 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 8604127 Medline TA: Dis Markers Country: Netherlands |
Other Details:
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Languages: eng Pagination: 129-38 Citation Subset: IM |
Affiliation:
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Hepatic Hemodynamic Laboratory, Liver Unit, Institut d'Investigacions Biomediques August Pi i Sunyer (IDIBAPS) and Centro de Investigación Biomédica en Red de Enfermedades Hepáticas y Digestivas (Ciberehd), Barcelona, Spain Ultrasound Section, Centre Diagnostic per la Imatge, Hospital Clinic i Provincial, Barcelona, Spain. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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