| Non-invasive detection of cocaine dissolved in wine bottles by (1) H magnetic resonance spectroscopy. | |
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MedLine Citation:
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PMID: 20886462 Owner: NLM Status: In-Data-Review |
Abstract/OtherAbstract:
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Recently, a number of cases of smuggling dissolved cocaine in wine bottles have been reported. The aim of the present study was to determine whether cocaine dissolved in wine can be detected by proton magnetic resonance spectroscopy ((1) H MRS) on a standard clinical MR scanner, in intact (i.e. unopened) wine bottles. (1) H MRS experiments were performed with a 3 Tesla clinical scanner on wine phantoms with or without cocaine contamination. The aromatic protons of cocaine displayed resonance peaks in the 7-8 ppm region of the spectrum, where no overlapping resonances of wine were present. Additional cocaine resonances were detected in the 2-3 ppm region of the spectrum, between the resonances of ethanol and other wine constituents. Detection of cocaine in wine (at 5 mM, i.e. ∼1.5 g/L) was feasible in a scan time of 1 min. We conclude that dissolved cocaine can be detected in intact wine bottles, on a standard clinical MR scanner. Thus, (1) H MRS is the technique of choice to examine this type of suspicious cargo, since it allows for a non-destructive and rapid content characterization. Copyright © 2010 John Wiley & Sons, Ltd. |
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Authors:
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Giulio Gambarota; Chiara Perazzolo; Antoine Leimgruber; Reto Meuli; Patrice Mangin; Marc Augsburger; Silke Grabherr |
Publication Detail:
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Type: Journal Article Date: 2010-09-30 |
Journal Detail:
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Title: Drug testing and analysis Volume: 3 ISSN: 1942-7611 ISO Abbreviation: Drug Test Anal Publication Date: 2011 Sep |
Date Detail:
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Created Date: 2011-09-30 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 101483449 Medline TA: Drug Test Anal Country: England |
Other Details:
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Languages: eng Pagination: 544-7 Citation Subset: IM |
Copyright Information:
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Copyright © 2010 John Wiley & Sons, Ltd. |
Affiliation:
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Physics Department, Swiss Federal Institute of Technology Lausanne, Switzerland. gambarota@gmail.com. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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