Document Detail


Non-invasive cardiac output measurement using a fast mixing box to measure carbon dioxide elimination.
MedLine Citation:
PMID:  18853584     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
This study investigated the accuracy of a new technique for measuring cardiac output using the derivative Fick principle based on the ratio of change in the partial pressures of end-tidal and mixed expired carbon dioxide produced by short periods of partial rebreathing. A prospective clinical study involving 24 patients following cardiopulmonary bypass for coronary artery bypass grafting or valvular surgery was undertaken in the intensive care unit of a university-affiliated hospital. Haemodynamic measurements were performed after admission to the intensive care unit. Cardiac output was measured simultaneously by bolus pulmonary artery thermodilution and by a non-invasive carbon dioxide partial rebreathing technique. Cardiac output measurement using the new technique demonstrated a significant but consistent underestimate, with a bias of -0.60 +/- 0.87 l/min. This new adaptation of the partial rebreathing technique is reliable in measuring cardiac output in postoperative patients. Reasons for the consistent discrepancy between thermodilution and partial rebreathing techniques are discussed.
Authors:
C J Killick; W G Parkin
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Publication Detail:
Type:  Clinical Trial; Journal Article    
Journal Detail:
Title:  Anaesthesia and intensive care     Volume:  36     ISSN:  0310-057X     ISO Abbreviation:  Anaesth Intensive Care     Publication Date:  2008 Sep 
Date Detail:
Created Date:  2008-10-15     Completed Date:  2009-01-14     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0342017     Medline TA:  Anaesth Intensive Care     Country:  Australia    
Other Details:
Languages:  eng     Pagination:  665-73     Citation Subset:  IM    
Affiliation:
Intensive Care Unit, Monash Medical Centre, Clayton, Victoria, Australia.
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MeSH Terms
Descriptor/Qualifier:
Adult
Aged
Aged, 80 and over
Carbon Dioxide / metabolism*
Cardiac Output / physiology*
Equipment Design
Female
Hemodynamics / physiology
Humans
Male
Middle Aged
Monitoring, Physiologic / instrumentation*
Prospective Studies
Reproducibility of Results
Respiration
Respiratory Mechanics / physiology
Thermodilution
Young Adult
Chemical
Reg. No./Substance:
124-38-9/Carbon Dioxide

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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