Document Detail

Non-invasive cardiac output measurement using a fast mixing box to measure carbon dioxide elimination.
MedLine Citation:
PMID:  18853584     Owner:  NLM     Status:  MEDLINE    
This study investigated the accuracy of a new technique for measuring cardiac output using the derivative Fick principle based on the ratio of change in the partial pressures of end-tidal and mixed expired carbon dioxide produced by short periods of partial rebreathing. A prospective clinical study involving 24 patients following cardiopulmonary bypass for coronary artery bypass grafting or valvular surgery was undertaken in the intensive care unit of a university-affiliated hospital. Haemodynamic measurements were performed after admission to the intensive care unit. Cardiac output was measured simultaneously by bolus pulmonary artery thermodilution and by a non-invasive carbon dioxide partial rebreathing technique. Cardiac output measurement using the new technique demonstrated a significant but consistent underestimate, with a bias of -0.60 +/- 0.87 l/min. This new adaptation of the partial rebreathing technique is reliable in measuring cardiac output in postoperative patients. Reasons for the consistent discrepancy between thermodilution and partial rebreathing techniques are discussed.
C J Killick; W G Parkin
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Publication Detail:
Type:  Clinical Trial; Journal Article    
Journal Detail:
Title:  Anaesthesia and intensive care     Volume:  36     ISSN:  0310-057X     ISO Abbreviation:  Anaesth Intensive Care     Publication Date:  2008 Sep 
Date Detail:
Created Date:  2008-10-15     Completed Date:  2009-01-14     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0342017     Medline TA:  Anaesth Intensive Care     Country:  Australia    
Other Details:
Languages:  eng     Pagination:  665-73     Citation Subset:  IM    
Intensive Care Unit, Monash Medical Centre, Clayton, Victoria, Australia.
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MeSH Terms
Aged, 80 and over
Carbon Dioxide / metabolism*
Cardiac Output / physiology*
Equipment Design
Hemodynamics / physiology
Middle Aged
Monitoring, Physiologic / instrumentation*
Prospective Studies
Reproducibility of Results
Respiratory Mechanics / physiology
Young Adult
Reg. No./Substance:
124-38-9/Carbon Dioxide

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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