Document Detail

Non invasive assessment of negative pressure wound therapy using high frequency diagnostic ultrasound: oedema reduction and new tissue accumulation.
MedLine Citation:
PMID:  22672782     Owner:  NLM     Status:  Publisher    
Tissue oedema plays an important role in the pathology of chronic and traumatic wounds. Negative pressure wound therapy (NPWT) is thought to contribute to active oedema reduction yet few studies have showed this effect. In this study high frequency diagnostic ultrasound at 20 MHz with an axial resolution of 60 µm was used to assess the effect of NPWT at - 80 mmHg on pressure ulcers and the surrounding tissue. Wounds were monitored in four patients over a 3-month period during which changes in oedema and wound bed thickness (granulation tissue) were measured non invasively. The results showed a rapid reduction of periwound tissue oedema in all patients with levels falling by a mean of 43% after 4 days of therapy. A 20% increase in the thickness of the wound bed was observed after 7 days due to new granulation tissue formation. Ultrasound scans through the in situ gauze NPWT filler also revealed the existence of macrodeformation in the tissue produced by the negative pressure. These preliminary studies suggest that non invasive assessment using high frequency diagnostic ultrasound could be a valuable tool in clinical studies of NPWT.
Stephen R Young; Sylvie Hampton; Robin Martin
Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2012-6-4
Journal Detail:
Title:  International wound journal     Volume:  -     ISSN:  1742-481X     ISO Abbreviation:  -     Publication Date:  2012 Jun 
Date Detail:
Created Date:  2012-6-7     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101230907     Medline TA:  Int Wound J     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Copyright Information:
© 2012 The Authors. International Wound Journal © 2012 Blackwell Publishing Ltd and Inc.
SR Young, PhD, Skin Science Consultancy, Duxford, Cambridge CB2 4RB, UK S Hampton, MA, RGN, Tissue Viability Consultancy Services, Eastbourne BN21 4RL, UK R Martin, PhD, Advanced Wound Devices Strategic Business Unit, Smith and Nephew Medical Ltd, PO Box 81, Hull HU3 2BN, UK.
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