Document Detail

Non-insulin-dependent diabetes in older patients. Complications and risk factors.
MedLine Citation:
PMID:  3535494     Owner:  NLM     Status:  MEDLINE    
Non-insulin-dependent diabetes mellitus is predominantly a disease of aging, with more than 70 percent of non-insulin-dependent (type II) diabetic patients older than 55 years of age. The prevalence of macrovascular, microvascular, and neurologic complications in outpatients with type II diabetes between the ages of 55 and 74 was compared with that in a similarly aged nondiabetic group of patients. The association between duration of diabetes, hypertension, age, and other putative risk factors that are prevalent in this elderly diabetic population and the occurrence of complications was explored. This cross-sectional survey confirmed a significant increase in retinopathy, neuropathy, impotence, and macrovascular complications in patients with type II diabetes. Within the diabetic population, duration of disease was associated with the occurrence of retinopathy and neuropathy, but not associated with such macrovascular complications as coronary artery disease. Gender, type of therapy, and previously identified risk factors for vascular disease such as hypertension had little impact on the prevalence of complications in this population. The notion that type II diabetes in the elderly represents "mild" diabetes with regard to complications must be discarded. Further identification of risk factors within this diabetic population may suggest therapeutic approaches that will prevent or ameliorate the development of complications.
D M Nathan; D E Singer; J E Godine; L C Perlmuter
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.; Research Support, U.S. Gov't, P.H.S.    
Journal Detail:
Title:  The American journal of medicine     Volume:  81     ISSN:  0002-9343     ISO Abbreviation:  Am. J. Med.     Publication Date:  1986 Nov 
Date Detail:
Created Date:  1986-12-04     Completed Date:  1986-12-04     Revised Date:  2007-11-15    
Medline Journal Info:
Nlm Unique ID:  0267200     Medline TA:  Am J Med     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  837-42     Citation Subset:  AIM; IM    
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MeSH Terms
Age Factors
Coronary Disease / complications
Diabetes Mellitus, Type 2 / complications*,  diet therapy,  drug therapy
Diabetic Neuropathies / complications
Diabetic Retinopathy / complications
Erectile Dysfunction / complications
Insulin / therapeutic use
Middle Aged
Prospective Studies
Sex Factors
Time Factors
Grant Support
Reg. No./Substance:
Erratum In:
Am J Med 1988 May;84(5):977

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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