Document Detail


Non-infectious pulmonary complications of myelodysplastic syndromes and chronic myeloproliferative disorders.
MedLine Citation:
PMID:  21742229     Owner:  NLM     Status:  In-Data-Review    
Abstract/OtherAbstract:
INTRODUCTION: Non-infectious pulmonary complications of myelodysplastic syndromes and chronic myeloproliferative disorders are not rare but remain little known to respiratory physicians who may be confronted with various clinical pictures corresponding to different pathophysiological causes. BACKGROUND: The few data in the literature only relate to isolated cases or small series. The non-infectious pulmonary complications of myelodysplastic syndromes and chronic myeloproliferative disorders can be classified into several clinical entities: tumour syndrome, pulmonary fibrosis or diffuse infiltrating pneumonia, autoimmune reactions including vasculitis, Sweet syndrome, organizing pneumonia, pulmonary alveolar proteinosis, pleural effusion and pulmonary arterial hypertension. The diagnosis is provided by the histology and management of these complications depends on the underlying pathology. VIEWPOINTS AND CONCLUSION: Myelodysplastic syndromes and myeloproliferative disorders are entities which are becoming better characterized and understood. Better knowledge of the pathophysiological mechanisms involved in these complications should improve their diagnosis and their management, which still remains complex.
Authors:
C Lamour; A Bergeron
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Publication Detail:
Type:  Journal Article     Date:  2011-06-08
Journal Detail:
Title:  Revue des maladies respiratoires     Volume:  28     ISSN:  1776-2588     ISO Abbreviation:  Rev Mal Respir     Publication Date:  2011 Jun 
Date Detail:
Created Date:  2011-07-11     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8408032     Medline TA:  Rev Mal Respir     Country:  France    
Other Details:
Languages:  eng     Pagination:  e18-27     Citation Subset:  IM    
Copyright Information:
Copyright © 2011. Published by Elsevier Masson SAS.
Affiliation:
Service de pneumologie, CHU de Poitiers, 2, rue de la Milétrie, 86021 Poitiers cedex, France.
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